PDF(Pubmed)
Abstract：
UNASSIGNED: Cilostazol has reported effectiveness for preventing aspiration pneumonia in patients with ischemic stroke, but whether it is similarly beneficial for patients with chronic limb-threatening ischemia (CLTI) is unclear.
UNASSIGNED: This retrospective single-center study enrolled 1,368 CLTI patients treated with endovascular therapy (EVT). In the multivariate analysis, predictors for aspiration pneumonia were age (hazard ratio [HR] 1.06 [95% confidence interval (CI) 1.03-1.10]), non-ambulatory status (HR 2.54 [95% CI 1.38-4.65]), the Geriatric Nutritional Risk Index (HR 0.97 [95% CI 0.95-0.99]), and cilostazol (HR 0.37 [95% CI 0.16-0.87]).
UNASSIGNED: Cilostazol administration reduced the risk of aspiration pneumonia in patients with CLTI undergoing EVT.
UNASSIGNED: This retrospective single-center study enrolled 1,368 CLTI patients treated with endovascular therapy (EVT). In the multivariate analysis, predictors for aspiration pneumonia were age (hazard ratio [HR] 1.06 [95% confidence interval (CI) 1.03-1.10]), non-ambulatory status (HR 2.54 [95% CI 1.38-4.65]), the Geriatric Nutritional Risk Index (HR 0.97 [95% CI 0.95-0.99]), and cilostazol (HR 0.37 [95% CI 0.16-0.87]).
UNASSIGNED: Cilostazol administration reduced the risk of aspiration pneumonia in patients with CLTI undergoing EVT.
摘要：
■西洛他唑已经报道了预防缺血性卒中患者吸入性肺炎的有效性，但它是否对慢性威胁肢体缺血(CLTI)患者同样有益尚不清楚.
■这项回顾性单中心研究纳入了1,368例接受血管内治疗（EVT）的CLTI患者。在多变量分析中，吸入性肺炎的预测因素为年龄(风险比[HR]1.06[95%置信区间(CI)1.03-1.10]),非动态状态（HR2.54[95%CI1.38-4.65]），老年营养风险指数(HR0.97[95%CI0.95-0.99])，和西洛他唑（HR0.37[95%CI0.16-0.87]）。
■西洛他唑可降低接受EVT的CLTI患者发生吸入性肺炎的风险。
■这项回顾性单中心研究纳入了1,368例接受血管内治疗（EVT）的CLTI患者。在多变量分析中，吸入性肺炎的预测因素为年龄(风险比[HR]1.06[95%置信区间(CI)1.03-1.10]),非动态状态（HR2.54[95%CI1.38-4.65]），老年营养风险指数(HR0.97[95%CI0.95-0.99])，和西洛他唑（HR0.37[95%CI0.16-0.87]）。
■西洛他唑可降低接受EVT的CLTI患者发生吸入性肺炎的风险。
