PDF(Pubmed)
Abstract：
Mitral regurgitation is the most common valvular disease, particularly in older adults. Recent literature has consistently supported that there are significant differences in mitral regurgitation outcomes between male and female patients and that this is likely multifactorial. Numerous sex differences in anatomy and pathophysiology may play a role in delayed diagnoses, referrals, and treatments for female patients. Despite the recognition of these discrepancies in the literature, many guidelines that steer clinical care do not incorporate these factors into society recommendations. Identifying and validating sex-specific diagnostic parameters and increasing the representation of female patients in trials of new mitral regurgitation treatment modalities are key factors in improving outcomes for female patients.
摘要：
二尖瓣返流是最常见的瓣膜疾病，尤其是老年人。最近的文献一致支持男性和女性患者在二尖瓣返流结果方面存在显著差异,并且这可能是多因素的。解剖学和病理生理学的许多性别差异可能在延迟诊断中起作用。转介,以及对女性患者的治疗。尽管文献中认识到了这些差异，许多指导临床护理的指南没有将这些因素纳入社会建议。在新的二尖瓣反流治疗模式的试验中，识别和验证性别特异性诊断参数以及增加女性患者的代表性是改善女性患者预后的关键因素。
