PDF(Pubmed)
Abstract：
Stress and anxiety may be found in patients with oral submucous fibrosis (OSMF), oral leukoplakia (OL) and oral lichen planus (OLP). Cortisol, sometimes referred to as the \"stress hormone,\" has been employed as a stress predictor. Therefore, it is of interest to estimate the levels of depression, anxiety and serum cortisol and establish correlation between them in patients with OL. OLP and OSMF. There were 240 patients, aged 20 years to 45 years, who were divided into four categories (OL, OSMF, OLP and control) of 60 patients apiece. In the supervision of a psychiatrist, the Hamilton Depression Rating Scale (HAM D) and Hamilton Anxiety Rating Scale (HAM (A) questionnaires were filled out. Five millilitres of venous blood were extracted using standard aseptic technique, and all of the samples were examined for serum cortisol level. Anxiety and depression was found in subjects of OL, OSMF and OLP at advanced stages. It was inferred that serum cortisol level was statistically correlated with depression and anxiety in patients with OL, OSMF and OLP.
摘要：
压力和焦虑可能在口腔粘膜下纤维化（OSMF）患者中发现，口腔白斑（OL）和口腔扁平苔藓（OLP）。皮质醇,有时被称为“压力荷尔蒙”，“已被用作压力预测因子。因此,估计抑郁的程度很有意义，焦虑和血清皮质醇，并建立他们之间的相关性。OLP和OSMF。有240名患者，年龄在20岁到45岁之间,他们被分为四类(OL，OSMF,OLP和对照）各60名患者。在精神病医生的监督下，填写汉密尔顿抑郁量表（HAMD）和汉密尔顿焦虑量表（HAM（A）问卷。使用标准无菌技术提取5毫升静脉血，并检查了所有样本的血清皮质醇水平。在OL的受试者中发现了焦虑和抑郁，OSMF和OLP处于高级阶段。由此推断血清皮质醇水平与OL患者抑郁、焦虑情绪有统计学相关性,OSMF和OLP。
