PDF(Pubmed)
Abstract：
UNASSIGNED: Anterior cervical discectomy and fusion (ACDF) has proven to be a clinically efficient and cost-effective method for treating patients with degenerative cervical spine conditions. New intervertebral implant products are being developed to improve fusion and stability while decreasing complications. This study assesses the effectiveness of Tritanium C (Tri-C) Anterior Cervical Cage (Stryker) in the treatment of degenerative disk disease (DDD) of the cervical spine compared with polyetheretherketone (PEEK) cages.
UNASSIGNED: A retrospective cohort analysis was conducted using data prospectively collected from two institutions. Patients who underwent ACDFs for DDD using either the Tri-C cage or PEEK cage were identified. The patients\' demographics, comorbidities, operative variables, and baseline patient-reported outcomes (PROs) were collected. PROs included the Neck Disability Index (NDI) and numeric rating scale (NRS) for neck and arm pain. The primary outcomes included 3- and 12-month PROs as well as the rates of 90-day readmission, 90-day reoperation, and perioperative complication. The radiographic outcomes included rates of subsidence, cage movement, and successful fusion within 12 months. Multivariate linear regression models were run to identify variables predictive of 12-month PROs.
UNASSIGNED: A total of 275 patients who underwent ACDF were included in this study and were divided into two groups: PEEK (n=213) and Tri-C (n=62). Both groups showed improvement in neck and arm pain and NDI postoperatively. When Tri-C and PEEK were compared, no significant differences were observed in the 3- or 12-month changes in neck or arm pain or NDI. Furthermore, there were no differences in the rates of 90-day readmission, 90-day reoperation, and perioperative complication. Regression analysis revealed that Tri-C vs. PEEK was not a significant predictor of any outcome.
UNASSIGNED: Our results indicate that the use of porous titanium Tri-C cage during ACDFs is an effective method for managing cervical DDD in terms of PROs, perioperative morbidity, and radiologic parameters. No significant difference was observed in any clinical outcome between patients undergoing ACDF using the Tri-C cage and those in whom the PEEK cage was used.
UNASSIGNED: III.
UNASSIGNED: A retrospective cohort analysis was conducted using data prospectively collected from two institutions. Patients who underwent ACDFs for DDD using either the Tri-C cage or PEEK cage were identified. The patients\' demographics, comorbidities, operative variables, and baseline patient-reported outcomes (PROs) were collected. PROs included the Neck Disability Index (NDI) and numeric rating scale (NRS) for neck and arm pain. The primary outcomes included 3- and 12-month PROs as well as the rates of 90-day readmission, 90-day reoperation, and perioperative complication. The radiographic outcomes included rates of subsidence, cage movement, and successful fusion within 12 months. Multivariate linear regression models were run to identify variables predictive of 12-month PROs.
UNASSIGNED: A total of 275 patients who underwent ACDF were included in this study and were divided into two groups: PEEK (n=213) and Tri-C (n=62). Both groups showed improvement in neck and arm pain and NDI postoperatively. When Tri-C and PEEK were compared, no significant differences were observed in the 3- or 12-month changes in neck or arm pain or NDI. Furthermore, there were no differences in the rates of 90-day readmission, 90-day reoperation, and perioperative complication. Regression analysis revealed that Tri-C vs. PEEK was not a significant predictor of any outcome.
UNASSIGNED: Our results indicate that the use of porous titanium Tri-C cage during ACDFs is an effective method for managing cervical DDD in terms of PROs, perioperative morbidity, and radiologic parameters. No significant difference was observed in any clinical outcome between patients undergoing ACDF using the Tri-C cage and those in whom the PEEK cage was used.
UNASSIGNED: III.
摘要：
■颈椎前路椎间盘切除术和融合术（ACDF）已被证明是一种临床上有效且具有成本效益的治疗颈椎退行性疾病的方法。正在开发新的椎间植入物产品，以改善融合和稳定性，同时减少并发症。这项研究评估了TritaniumC（Tri-C）颈椎前笼（Stryker）与聚醚醚酮（PEEK）笼相比，在治疗颈椎退行性椎间盘疾病（DDD）中的有效性。
■使用从两个机构前瞻性收集的数据进行回顾性队列分析。确定使用Tri-C笼或PEEK笼接受DDD的ACDFs的患者。病人的人口统计学，合并症,操作变量，收集基线患者报告结果(PRO).PROs包括颈部残疾指数（NDI）和颈部和手臂疼痛的数字评定量表（NRS）。主要结果包括3个月和12个月的PRO以及90天的再入院率，90天再次手术,围手术期并发症。放射学结果包括沉降率，保持架运动,并在12个月内成功融合。运行多元线性回归模型以确定预测12个月PRO的变量。
■共有275例接受ACDF的患者纳入本研究，分为两组：PEEK（n=213）和Tri-C（n=62）。两组术后颈部和手臂疼痛及NDI均有改善。当比较Tri-C和PEEK时，在3个月或12个月的颈部或手臂疼痛或NDI的变化中没有观察到显著差异.此外，90天再入院率没有差异，90天再次手术,围手术期并发症。回归分析显示，Tri-C与PEEK不是任何结果的重要预测因子。
■我们的结果表明，在ACDFs期间使用多孔钛Tri-C笼是在PRO方面管理宫颈DDD的有效方法，围手术期发病率，和放射学参数。在使用Tri-C笼进行ACDF的患者和使用PEEK笼的患者之间,在任何临床结果中没有观察到显著差异。
■III.
■使用从两个机构前瞻性收集的数据进行回顾性队列分析。确定使用Tri-C笼或PEEK笼接受DDD的ACDFs的患者。病人的人口统计学，合并症,操作变量，收集基线患者报告结果(PRO).PROs包括颈部残疾指数（NDI）和颈部和手臂疼痛的数字评定量表（NRS）。主要结果包括3个月和12个月的PRO以及90天的再入院率，90天再次手术,围手术期并发症。放射学结果包括沉降率，保持架运动,并在12个月内成功融合。运行多元线性回归模型以确定预测12个月PRO的变量。
■共有275例接受ACDF的患者纳入本研究，分为两组：PEEK（n=213）和Tri-C（n=62）。两组术后颈部和手臂疼痛及NDI均有改善。当比较Tri-C和PEEK时，在3个月或12个月的颈部或手臂疼痛或NDI的变化中没有观察到显著差异.此外，90天再入院率没有差异，90天再次手术,围手术期并发症。回归分析显示，Tri-C与PEEK不是任何结果的重要预测因子。
■我们的结果表明，在ACDFs期间使用多孔钛Tri-C笼是在PRO方面管理宫颈DDD的有效方法，围手术期发病率，和放射学参数。在使用Tri-C笼进行ACDF的患者和使用PEEK笼的患者之间,在任何临床结果中没有观察到显著差异。
■III.
