PDF(Pubmed)
Abstract：
Autoimmune encephalitis (AE) is a rare immune-mediated disorder comprised of non-infectious neuroinflammatory disease processes. Clinical presentation overlaps with a broad range of neurodegenerative disorders and infectious encephalitis; therefore, AE remains a diagnosis of exclusion. Patients may present with nonspecific symptoms such as psychiatric disturbances, cognitive deficits, seizures, movement disorders, and confusion. Prompt diagnosis and management are necessary for patients with AE to decrease mortality and improve quality of life. First-line therapy includes immunosuppression with corticosteroids, intravenous immunoglobulin, and plasmapheresis. We report the case of an 86-year-old female with a medical history of Parkinson\'s disease who presented with nonspecific seizure-like activity and was diagnosed with AE.
摘要：
自身免疫性脑炎（AE）是一种罕见的免疫介导的疾病，由非感染性神经炎性疾病过程组成。临床表现与广泛的神经退行性疾病和感染性脑炎重叠；因此，AE仍然是排除的诊断。患者可能会出现非特异性症状，如精神障碍，认知缺陷,癫痫发作,运动障碍,和困惑。及时的诊断和治疗对于AE患者降低死亡率和改善生活质量是必要的。一线治疗包括皮质类固醇的免疫抑制，静脉注射免疫球蛋白，和血浆置换.我们报告了一名86岁女性，有帕金森病病史，表现为非特异性癫痫样活动，并被诊断为AE。
