关键词: abstinence drug abuse finnegan heroin neonate nicotine phenobarbitone pregnancy psychotropics

来  源:   DOI:10.7759/cureus.64372   PDF(Pubmed)

Abstract:
The increasing prevalence of substance misuse in modern culture is contributing to the growth in neonatal abstinence syndrome (NAS) cases in India. NAS can be challenging to diagnose due to nonspecific symptoms and maternal suppression of drug history. Only a few reports of NAS have been published from India. This is a case series of three newborns from India who all had symptoms like restlessness, high-pitched crying, excessive sweating, vigorous sucking, tremors, and diarrhea. The investigations did not lead to any conclusions. In the first case, the mother was treated with a combination of psychotropic medications, including selective serotonin reuptake inhibitors (SSRIs), atypical antipsychotics, and tricyclic antidepressants. In the second case, the mother was a nicotine addict, while in the third case, the mother had an opiate addiction. It was only after being asked several times that the abuse background of the last two cases was revealed. As a result, three cases of NAS were diagnosed, successfully managed with phenobarbitone, and discharged.
摘要:
在现代文化中,滥用药物的患病率越来越高,这导致了印度新生儿禁欲综合症(NAS)病例的增长。由于非特异性症状和母体对药物史的抑制,NAS的诊断可能具有挑战性。印度仅发布了一些NAS报告。这是三个来自印度的新生儿的病例系列,他们都有不安的症状,高声哭泣,出汗过多,剧烈的吸吮,震颤,和腹泻。调查没有得出任何结论。在第一种情况下,母亲接受了精神药物的组合治疗,包括选择性5-羟色胺再摄取抑制剂(SSRIs),非典型抗精神病药,和三环抗抑郁药.在第二种情况下,母亲是个尼古丁瘾君子,而在第三种情况下,母亲有鸦片成瘾。在被询问了几次之后,最后两个案件的虐待背景才被揭露出来。因此,诊断为3例NAS,用苯巴比妥成功管理,并出院。
公众号