PDF(Pubmed)
Abstract：
Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) is a rare central nervous system inflammatory condition usually presenting with a range of symptoms, including ataxia, diplopia, dysarthria, seizures, and headaches. We present a unique case of a 22-year-old woman exhibiting headache as the sole symptom. Imaging and biopsy confirmed the diagnosis, and initial steroid treatment provided relief, though it relapsed on tapering. Long-term management with low-dose steroids and mycophenolate mofetil achieved remission. This case highlights the importance of recognizing atypical presentations of CLIPPERS, emphasizing the need for prompt diagnosis and appropriate treatment plans to improve patient outcomes. Further research is necessary to enhance our understanding and management of CLIPPERS.
摘要：
慢性淋巴细胞炎症伴脑桥血管周围增强对类固醇反应（CLIPPERS）是一种罕见的中枢神经系统炎症，通常表现为一系列症状，包括共济失调,复视,构音障碍,癫痫发作,和头痛。我们介绍了一名22岁女性的独特病例，其唯一症状是头痛。影像学和活检证实了诊断，最初的类固醇治疗提供了缓解，尽管它在逐渐缩小时会复发。低剂量类固醇和霉酚酸酯的长期管理可缓解。这个案例强调了识别CLIPPERS非典型表现的重要性，强调需要及时诊断和适当的治疗计划，以改善患者的预后。需要进一步的研究，以增强我们对CLIPPERS的理解和管理。
