PDF(Pubmed)
Abstract：
Idiopathic thrombocytopenic purpura (ITP) is characterized by a persistently low platelet count, which can lead to serious bleeding such as gastritis and hemorrhagic stroke. The formation of auto-antibodies in ITP leads to increased destruction of platelets and then hampers hematopoiesis. Corticosteroids and intravenous immunoglobulin are among the common treatments used for ITP, but they have significant side effects. This is a case report of a 27-year-old woman with ITP who was found to be anemic, thrombocytopenic, and had a ruptured ovarian cyst after the initial romiplostim therapy. The patient benefited from fluid resuscitation, blood transfusion, and corticosteroid therapy; then, the patient\'s condition improved. This case highlights the complications associated with managing ITP, emphasizing the importance of personalizing therapy regimens through regular monitoring to improve the balance of benefits and risk, resulting in a comprehensive treatment for chronic patients suffering from ITP.
摘要：
特发性血小板减少性紫癜（ITP）的特征是持续的低血小板计数，这可能导致严重出血，如胃炎和出血性中风。ITP中自身抗体的形成导致血小板破坏增加,然后阻碍造血。皮质类固醇和静脉注射免疫球蛋白是用于ITP的常见治疗方法，但是它们有明显的副作用。这是一例27岁女性ITP患者贫血的病例报告,血小板减少性,初次接受romiplostim治疗后卵巢囊肿破裂。病人从液体复苏中受益，输血,和皮质类固醇治疗；然后，病人的病情好转了。这个案例突出了与管理ITP相关的并发症，强调通过定期监测个性化治疗方案的重要性，以改善获益和风险的平衡，从而为患有ITP的慢性患者提供了综合治疗。
