PDF(Pubmed)
Abstract：
UNASSIGNED: Rhinosinusitis disability index (RSDI) questionnaire is used to assess the severity of chronic rhinosinusitis (CRS) from the patient\'s perspective. The severity of CRS can be measured objectively with the endoscope and computed tomogram (CT) using the Lund-Kennedy endoscopic score and Mackay-Lund scores respectively. The objective of the study is to evaluate whether baseline RSDI and Lund-Kennedy (LK) endoscopy scoring can help predict the Mackay-Lund CT (MKLCT) scores after medical treatment in patients with CRS.
UNASSIGNED: This is a prospective, observational study, carried out from 1st October 2017 to 30th September 2019 in the ENT out- patient department at a tertiary hospital in Northern India. 90 patients diagnosed with CRS were enrolled consecutively in the study. RSDI questionnaire was filled out for all the participants. They all underwent a diagnostic endoscopy and CRS was graded according to the Lund-Kennedy endoscopic scores. All participants were given medical treatment. Patients underwent CT of the paranasal sinuses after medical treatment and the MLKCT scores were calculated. The baseline RSDI and Lund-Kennedy scores were correlated with the MKLCT scores using Spearman\'s Rank correlation tests. The diagnostic ability of the RSDI and LK endoscopy scores to predict the least MKLCT scores was compared using the receiver operator characteristics curves (ROC).
UNASSIGNED: A statistically significant correlation was seen with LK endoscopy scores and MKLCT scores (r = 0.396, p < 0.001) Among the individual parameters of the LK endoscopy scores only the polyp score had a statistically significant correlation with MKLCT scores (r = 0.593, p < 0.001). A weak negative correlation (r = - 0.058, p = 0.586) was seen between the RSDI scores and MKLCT scores. AUC in ROC curves for a LK endoscopy scores and RSDI scores were 0.690 and 0.462 respectively. Cut-off for predicting a MKLCT score of one or more for RSDI score was 25, with a sensitivity of 61% and specificity of 38.5%. Similarly, the cut-off for LK endoscopic score was 4.5, with a sensitivity of 68.8% and specificity of 61.5%.
UNASSIGNED: Statistically significant (p < 0.001) association was found between baseline Lund-Kennedy endoscopic scores and Mackay-Lund CT scores post medical treatment. No significant association was found between RSDI scores and Mackay-Lund CT scores. ROC analysis indicated that Lund- Kennedy endoscopy score is a more accurate tool than RSDI score to predict a Mackay-Lund CT scores after medical treatment.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-024-04708-6.
UNASSIGNED: This is a prospective, observational study, carried out from 1st October 2017 to 30th September 2019 in the ENT out- patient department at a tertiary hospital in Northern India. 90 patients diagnosed with CRS were enrolled consecutively in the study. RSDI questionnaire was filled out for all the participants. They all underwent a diagnostic endoscopy and CRS was graded according to the Lund-Kennedy endoscopic scores. All participants were given medical treatment. Patients underwent CT of the paranasal sinuses after medical treatment and the MLKCT scores were calculated. The baseline RSDI and Lund-Kennedy scores were correlated with the MKLCT scores using Spearman\'s Rank correlation tests. The diagnostic ability of the RSDI and LK endoscopy scores to predict the least MKLCT scores was compared using the receiver operator characteristics curves (ROC).
UNASSIGNED: A statistically significant correlation was seen with LK endoscopy scores and MKLCT scores (r = 0.396, p < 0.001) Among the individual parameters of the LK endoscopy scores only the polyp score had a statistically significant correlation with MKLCT scores (r = 0.593, p < 0.001). A weak negative correlation (r = - 0.058, p = 0.586) was seen between the RSDI scores and MKLCT scores. AUC in ROC curves for a LK endoscopy scores and RSDI scores were 0.690 and 0.462 respectively. Cut-off for predicting a MKLCT score of one or more for RSDI score was 25, with a sensitivity of 61% and specificity of 38.5%. Similarly, the cut-off for LK endoscopic score was 4.5, with a sensitivity of 68.8% and specificity of 61.5%.
UNASSIGNED: Statistically significant (p < 0.001) association was found between baseline Lund-Kennedy endoscopic scores and Mackay-Lund CT scores post medical treatment. No significant association was found between RSDI scores and Mackay-Lund CT scores. ROC analysis indicated that Lund- Kennedy endoscopy score is a more accurate tool than RSDI score to predict a Mackay-Lund CT scores after medical treatment.
UNASSIGNED: The online version contains supplementary material available at 10.1007/s12070-024-04708-6.
摘要：
■鼻-鼻窦炎残疾指数（RSDI）问卷用于从患者的角度评估慢性鼻-鼻窦炎（CRS）的严重程度。CRS的严重程度可以用内窥镜和计算机断层扫描（CT）分别使用Lund-Kennedy内窥镜评分和Mackay-Lund评分客观地测量。该研究的目的是评估基线RSDI和Lund-Kennedy（LK）内窥镜检查评分是否可以帮助预测CRS患者接受药物治疗后的Mackay-LundCT（MKLCT）评分。
■这是一个前景，观察性研究，2017年10月1日至2019年9月30日在印度北部一家三级医院的耳鼻喉科门诊部进行。90例被诊断为CRS的患者被连续纳入研究。为所有参与者填写了RSDI问卷。他们都接受了诊断性内窥镜检查，CRS根据Lund-Kennedy内窥镜评分进行分级。所有参与者均接受药物治疗。患者在药物治疗后接受鼻旁窦CT检查，并计算MLKCT评分。基线RSDI和Lund-Kennedy评分与MKLCT评分采用Spearman的等级相关检验。使用受试者操作员特征曲线（ROC）比较了RSDI和LK内窥镜检查评分预测最小MKLCT评分的诊断能力。
■与LK内窥镜检查评分和MKLCT评分具有统计学上的显着相关性（r=0.396，p<0.001）在LK内窥镜检查评分的各个参数中，只有息肉评分与MKLCT评分具有统计学上的显着相关性（r=0.593，p<0.001）。在RSDI评分和MKLCT评分之间观察到弱负相关(r=-0.058,p=0.586)。LK内镜评分和RSDI评分的ROC曲线AUC分别为0.690和0.462。预测RSDI评分的一个或多个MKLCT评分的截止值为25，敏感性为61％，特异性为38.5％。同样，LK内镜评分的临界值为4.5,敏感性为68.8%,特异性为61.5%.
■在基线Lund-Kennedy内窥镜评分和药物治疗后Mackay-LundCT评分之间发现统计学上显著(p<0.001)的关联。在RSDI评分和Mackay-LundCT评分之间没有发现显着关联。ROC分析表明，Lund-Kennedy内窥镜检查评分比RSDI评分更准确，可以预测药物治疗后的Mackay-LundCT评分。
■在线版本包含补充材料，可在10.1007/s12070-024-04708-6获得。
■这是一个前景，观察性研究，2017年10月1日至2019年9月30日在印度北部一家三级医院的耳鼻喉科门诊部进行。90例被诊断为CRS的患者被连续纳入研究。为所有参与者填写了RSDI问卷。他们都接受了诊断性内窥镜检查，CRS根据Lund-Kennedy内窥镜评分进行分级。所有参与者均接受药物治疗。患者在药物治疗后接受鼻旁窦CT检查，并计算MLKCT评分。基线RSDI和Lund-Kennedy评分与MKLCT评分采用Spearman的等级相关检验。使用受试者操作员特征曲线（ROC）比较了RSDI和LK内窥镜检查评分预测最小MKLCT评分的诊断能力。
■与LK内窥镜检查评分和MKLCT评分具有统计学上的显着相关性（r=0.396，p<0.001）在LK内窥镜检查评分的各个参数中，只有息肉评分与MKLCT评分具有统计学上的显着相关性（r=0.593，p<0.001）。在RSDI评分和MKLCT评分之间观察到弱负相关(r=-0.058,p=0.586)。LK内镜评分和RSDI评分的ROC曲线AUC分别为0.690和0.462。预测RSDI评分的一个或多个MKLCT评分的截止值为25，敏感性为61％，特异性为38.5％。同样，LK内镜评分的临界值为4.5,敏感性为68.8%,特异性为61.5%.
■在基线Lund-Kennedy内窥镜评分和药物治疗后Mackay-LundCT评分之间发现统计学上显著(p<0.001)的关联。在RSDI评分和Mackay-LundCT评分之间没有发现显着关联。ROC分析表明，Lund-Kennedy内窥镜检查评分比RSDI评分更准确，可以预测药物治疗后的Mackay-LundCT评分。
■在线版本包含补充材料，可在10.1007/s12070-024-04708-6获得。
