PDF(Pubmed)
Abstract：
Adenoid cystic carcinoma (ACC) is an uncommon malignant neoplasm that predominantly arises from major and minor salivary glands, accounting for about 1% of head and neck malignancies. ACCs originating from the pterygopalatine fossa (PPF) are extremely rare. In this case report, we present a 77-year-old male patient who experienced a two-year hemi-facial numbness and mild trismus, with intact nasal mucosa. He underwent Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) which revealed opacification of the left PPF with extension to the left infratemporal fossa and osteolytic areas of the sphenoid bone. Histopathology, following blind biopsies, revealed ACC of the PPF, which was subsequently treated with combined therapy (radiotherapy and chemotherapy). Due to their slow and progressive growth, as well as their tendency for perineural invasion, ACCs should always be considered in the differential diagnosis of painless swelling or nerve dysfunction. To our knowledge, this case is the fifth described in the English literature.
摘要：
腺样囊性癌（ACC）是一种罕见的恶性肿瘤，主要来自主要和次要唾液腺。约占头颈部恶性肿瘤的1%。源自翼腭窝（PPF）的ACCs极为罕见。在这个案例报告中,我们介绍了一名77岁的男性患者，他经历了两年的半面部麻木和轻度的三端肌，鼻粘膜完整。他接受了计算机断层扫描（CT）和磁共振成像（MRI）检查，显示左PPF浑浊，并延伸到左颞下窝和蝶骨的溶骨区。组织病理学,盲目活检后，揭示了PPF的ACC，随后接受联合治疗（放疗和化疗）。由于他们缓慢而渐进的增长，以及他们的神经周侵袭倾向，无痛性肿胀或神经功能障碍的鉴别诊断应始终考虑ACCs。据我们所知,这是英语文献中描述的第五个案例。
