关键词: CPAP Induced Facial Discomfort Continuous Positive Airway Pressure Lidocaine-prilocaine Cream Obstructive Sleep Apnea mask

来  源:   DOI:10.1007/s12070-024-04731-7   PDF(Pubmed)

Abstract:
UNASSIGNED: Despite the high efficacy of using Continuous positive airway pressure (CPAP) in reversing upper airway obstruction in obstructive sleep apnea (OSA), the efficiency of this treatment is limited due to the low adherence. Mask pressure is suggested to play a significant role in adherence. In this study, we intend to investigate the effect of Lidocaine-prilocaine cream CPAP mask on pressure sensation.
UNASSIGNED: In this study, 75 patients referred to CPAP titration were divided into three groups. In groups one and two, Lidocaine-prilocaine cream and Petroleum jelly were used respectively. The third group had no intervention.
UNASSIGNED: VAS discomfort immediately (VAS0), after 15 min (VAS15), and the next day (VAS all) in three groups were compared. VAS0, VAS15, and VAS all were not significantly different among the three groups (P > 0.05). Among participants with VAS0 above 5, VAS15 was significantly lower in intervention groups than the control group (P < 0.05).
UNASSIGNED: This study shows that both Petroleum jelly and Lidocaine-prilocaine cream can be used for decreasing pressure sensation during CPAP titration among patients who suffer excessive facial discomfort immediately after putting on a CPAP mask.
摘要:
尽管使用持续气道正压通气(CPAP)逆转阻塞性睡眠呼吸暂停(OSA)的上气道阻塞具有很高的疗效,这种治疗的效率是有限的,由于低坚持。建议面罩压力在依从性中起重要作用。在这项研究中,我们打算研究利多卡因-丙胺卡因乳膏CPAP面膜对压力感觉的影响。
在这项研究中,75例CPAP滴定患者分为三组。在第一组和第二组中,分别使用利多卡因-丙胺卡因乳膏和凡士林。第三组无干预。
立即VAS不适(VAS0),15分钟后(VAS15),并于次日(全部VAS)对三组进行比较。3组间VAS0、VAS15、VAS均无统计学差异(P>0.05)。在VAS0≥5的参与者中,干预组的VAS15明显低于对照组(P<0.05)。
这项研究表明,凡士林和利多卡因-丙胺卡因乳膏均可用于在戴上CPAP面罩后立即遭受过度面部不适的患者在CPAP滴定过程中降低压力感觉。
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