PDF(Pubmed)
Abstract：
UNASSIGNED: Coronary artery disease (CAD) and herpes zoster represent significant health burdens, and their potential interrelationships remain understudied. This cohort study aimed to address the existing knowledge gap by systematically exploring whether people with CAD are at increased risk for developing herpes zoster.
UNASSIGNED: Using the 2006-2015 claims data of the National Health Insurance Program in Taiwan, we identified participants aged ≥20 years with a new diagnosis of CAD as the CAD group. We selected sex- and age-matched participants without CAD as the non-CAD group. The incidence rate of herpes zoster at the end of follow-up was calculated. A multivariable Cox proportional hazards regression model was used to measure the hazard ratio and 95% CI for herpes zoster associated with covariables.
UNASSIGNED: The overall incidence rate of herpes zoster was 1.14-fold greater in the CAD group as compared with the non-CAD group (6.52 vs 5.74 per 1000 person-years; 95% CI, 1.08-1.20). After controlling for covariables, the adjusted hazard ratio of herpes zoster was 1.21 (95% CI, 1.14-1.27) for the CAD group as compared with the non-CAD group.
UNASSIGNED: This cohort study provides valuable insights into the potential association between CAD and the risk of developing herpes zoster. The findings may have implications for preventive strategies of herpes zoster in people with CAD. Further research and collaboration with diverse groups will be critical to validate and extend our findings.
UNASSIGNED: Using the 2006-2015 claims data of the National Health Insurance Program in Taiwan, we identified participants aged ≥20 years with a new diagnosis of CAD as the CAD group. We selected sex- and age-matched participants without CAD as the non-CAD group. The incidence rate of herpes zoster at the end of follow-up was calculated. A multivariable Cox proportional hazards regression model was used to measure the hazard ratio and 95% CI for herpes zoster associated with covariables.
UNASSIGNED: The overall incidence rate of herpes zoster was 1.14-fold greater in the CAD group as compared with the non-CAD group (6.52 vs 5.74 per 1000 person-years; 95% CI, 1.08-1.20). After controlling for covariables, the adjusted hazard ratio of herpes zoster was 1.21 (95% CI, 1.14-1.27) for the CAD group as compared with the non-CAD group.
UNASSIGNED: This cohort study provides valuable insights into the potential association between CAD and the risk of developing herpes zoster. The findings may have implications for preventive strategies of herpes zoster in people with CAD. Further research and collaboration with diverse groups will be critical to validate and extend our findings.
摘要：
■冠状动脉疾病（CAD）和带状疱疹代表了巨大的健康负担，它们潜在的相互关系仍未得到充分研究。这项队列研究旨在通过系统地探索CAD患者是否有增加的患带状疱疹的风险来解决现有的知识差距。
■使用台湾国民健康保险计划的2006-2015年索赔数据，我们将新诊断为CAD的年龄≥20岁的参与者确定为CAD组.我们选择没有CAD的性别和年龄匹配的参与者作为非CAD组。计算随访结束时带状疱疹的发生率。使用多变量Cox比例风险回归模型来测量与协变量相关的带状疱疹的风险比和95％CI。
与非CAD组相比，CAD组带状疱疹的总发病率高1.14倍（6.52vs5.74/1000人年；95％CI，1.08-1.20）。在控制了协变量之后，与非CAD组相比,CAD组带状疱疹的校正风险比为1.21(95%CI,1.14~1.27).
这项队列研究为CAD与带状疱疹发病风险之间的潜在关联提供了有价值的见解。这些发现可能对CAD患者带状疱疹的预防策略有影响。与不同团体的进一步研究和合作对于验证和扩展我们的发现至关重要。
■使用台湾国民健康保险计划的2006-2015年索赔数据，我们将新诊断为CAD的年龄≥20岁的参与者确定为CAD组.我们选择没有CAD的性别和年龄匹配的参与者作为非CAD组。计算随访结束时带状疱疹的发生率。使用多变量Cox比例风险回归模型来测量与协变量相关的带状疱疹的风险比和95％CI。
与非CAD组相比，CAD组带状疱疹的总发病率高1.14倍（6.52vs5.74/1000人年；95％CI，1.08-1.20）。在控制了协变量之后，与非CAD组相比,CAD组带状疱疹的校正风险比为1.21(95%CI,1.14~1.27).
这项队列研究为CAD与带状疱疹发病风险之间的潜在关联提供了有价值的见解。这些发现可能对CAD患者带状疱疹的预防策略有影响。与不同团体的进一步研究和合作对于验证和扩展我们的发现至关重要。
