PDF(Pubmed)
Abstract：
UNASSIGNED: Methamphetamine is an emerging drug threat. The disparity in cardiomyopathy-associated hospital admissions among methamphetamine users (CAHMA) over the decade remains unknown.
UNASSIGNED: The purpose of this study was to determine the trends and prevalence of CAHMA by age, sex, race, and geographical region.
UNASSIGNED: We used data from 2008 to 2020 from the National Inpatient Sample database. We identified 12,845,919 cardiomyopathy-associated hospital admissions; among them, 222,727 were diagnosed as methamphetamine users. A generalized linear model with binomial link function was used to compute the prevalence ratio and 95% CI. Those who used other substances along with methamphetamine were excluded from the analysis.
UNASSIGNED: CAHMA increased by 231% (P trend <0.001) from 2008 to 2020. CAHMA increased 345% for men (P trend <0.001) and 122% for women (P trend <0.001), 271% for non-Hispanic White (P trend <0.001), 254% for non-Hispanic Black (p trend <0.001), 565% for Hispanic (P trend <0.001), and 645% for non-Hispanic Asian (P trend <0.001) population. CAHMA also increased significantly in the West region (530%) (P trend <0.001) and South region (200%) (P trend <0.001) of the United States. Men, Hispanic population, age groups 26 to 40 and 41 to 64 years, and Western regions showed a significantly higher uptrend than their counterparts (P trend <0.001).
UNASSIGNED: CAHMA have increased significantly in the United States. Men, Hispanics, non-Hispanic Asian, age groups 41 to 64. and western regions showed a higher proportional increase highlighting gender-based, racial/ethnic, and regional disparities over the study period.
UNASSIGNED: The purpose of this study was to determine the trends and prevalence of CAHMA by age, sex, race, and geographical region.
UNASSIGNED: We used data from 2008 to 2020 from the National Inpatient Sample database. We identified 12,845,919 cardiomyopathy-associated hospital admissions; among them, 222,727 were diagnosed as methamphetamine users. A generalized linear model with binomial link function was used to compute the prevalence ratio and 95% CI. Those who used other substances along with methamphetamine were excluded from the analysis.
UNASSIGNED: CAHMA increased by 231% (P trend <0.001) from 2008 to 2020. CAHMA increased 345% for men (P trend <0.001) and 122% for women (P trend <0.001), 271% for non-Hispanic White (P trend <0.001), 254% for non-Hispanic Black (p trend <0.001), 565% for Hispanic (P trend <0.001), and 645% for non-Hispanic Asian (P trend <0.001) population. CAHMA also increased significantly in the West region (530%) (P trend <0.001) and South region (200%) (P trend <0.001) of the United States. Men, Hispanic population, age groups 26 to 40 and 41 to 64 years, and Western regions showed a significantly higher uptrend than their counterparts (P trend <0.001).
UNASSIGNED: CAHMA have increased significantly in the United States. Men, Hispanics, non-Hispanic Asian, age groups 41 to 64. and western regions showed a higher proportional increase highlighting gender-based, racial/ethnic, and regional disparities over the study period.
摘要：
■甲基苯丙胺是一种新兴的毒品威胁。十年来，甲基苯丙胺使用者（CAHMA）与心肌病相关的住院人数差异仍然未知。
■本研究的目的是按年龄确定CAHMA的趋势和患病率，性别,种族,和地理区域。
■我们使用了来自国家住院患者样本数据库的2008年至2020年的数据。我们确定了12,845,919名心肌病相关的住院患者；其中，222,727人被诊断为甲基苯丙胺使用者。使用具有二项链接函数的广义线性模型来计算患病率和95％CI。那些与甲基苯丙胺一起使用其他物质的人被排除在分析之外。
■从2008年到2020年，CAHMA增长了231%（P趋势<0.001）。男性CAHMA增加345%（P趋势<0.001），女性增加122%（P趋势<0.001），非西班牙裔白人为271%（P趋势<0.001），非西班牙裔黑人为254%（p趋势<0.001），西班牙裔占565%（P趋势<0.001），非西班牙裔亚洲人群为645%(P趋势<0.001)。美国西部地区(530%)(P趋势<0.001)和南部地区(200%)(P趋势<0.001)的CAHMA也显著增加。男人,西班牙裔人口，年龄组26至40岁和41至64岁，西部地区的上升趋势明显高于西部地区（P<0.001）。
■CAHMA在美国显著增加。男人,西班牙裔,非西班牙裔亚洲人，年龄组41至64。西部地区显示出更高的比例增长，突出了基于性别的增长，种族/民族,以及研究期间的地区差异。
■本研究的目的是按年龄确定CAHMA的趋势和患病率，性别,种族,和地理区域。
■我们使用了来自国家住院患者样本数据库的2008年至2020年的数据。我们确定了12,845,919名心肌病相关的住院患者；其中，222,727人被诊断为甲基苯丙胺使用者。使用具有二项链接函数的广义线性模型来计算患病率和95％CI。那些与甲基苯丙胺一起使用其他物质的人被排除在分析之外。
■从2008年到2020年，CAHMA增长了231%（P趋势<0.001）。男性CAHMA增加345%（P趋势<0.001），女性增加122%（P趋势<0.001），非西班牙裔白人为271%（P趋势<0.001），非西班牙裔黑人为254%（p趋势<0.001），西班牙裔占565%（P趋势<0.001），非西班牙裔亚洲人群为645%(P趋势<0.001)。美国西部地区(530%)(P趋势<0.001)和南部地区(200%)(P趋势<0.001)的CAHMA也显著增加。男人,西班牙裔人口，年龄组26至40岁和41至64岁，西部地区的上升趋势明显高于西部地区（P<0.001）。
■CAHMA在美国显著增加。男人,西班牙裔,非西班牙裔亚洲人，年龄组41至64。西部地区显示出更高的比例增长，突出了基于性别的增长，种族/民族,以及研究期间的地区差异。
