PDF(Pubmed)
Abstract：
UNASSIGNED: We sought to investigate the impact of stenting on native patent ductus arteriosus (PDA) length, curvature, and pulsatile deformations in patients with ductal-dependent pulmonary circulations.
UNASSIGNED: Patients with PDA stents who received contrast-enhanced 3-dimensional computed tomography with a view of the PDA, thoracic aorta, and pulmonary arteries were retrospectively included in this study. Geometric models of the prestented and poststented PDA were constructed from the computed tomography images, and PDA arclength, curvature, and pulsatile deformations were quantified.
UNASSIGNED: A total of 12 patients with cyanotic congenital heart disease were included, 10 of whom received 1 stent in the PDA and 2 received multiple overlapping stents. From prestenting to poststenting, the PDA shortened by 26 ± 18% (P = .004) and decreased in mean and peak curvature by 60 ± 21% and 68 ± 15%, respectively (both P < .001). Pulsatile deformations varied highly for the native PDA, stented PDA, and stents themselves.
UNASSIGNED: The shortening and straightening of the PDA after stenting are significant and substantial, and their quantitative characterization will enable interventionalists to select stent lengths that span the entire PDA without encroaching on the aortic or pulmonary artery, which could cause hemodynamic interference, stent kink, and fatigue. Pulsatile PDA deformations can be used to design and evaluate devices tailored to congenital heart disease in neonates.
UNASSIGNED: Patients with PDA stents who received contrast-enhanced 3-dimensional computed tomography with a view of the PDA, thoracic aorta, and pulmonary arteries were retrospectively included in this study. Geometric models of the prestented and poststented PDA were constructed from the computed tomography images, and PDA arclength, curvature, and pulsatile deformations were quantified.
UNASSIGNED: A total of 12 patients with cyanotic congenital heart disease were included, 10 of whom received 1 stent in the PDA and 2 received multiple overlapping stents. From prestenting to poststenting, the PDA shortened by 26 ± 18% (P = .004) and decreased in mean and peak curvature by 60 ± 21% and 68 ± 15%, respectively (both P < .001). Pulsatile deformations varied highly for the native PDA, stented PDA, and stents themselves.
UNASSIGNED: The shortening and straightening of the PDA after stenting are significant and substantial, and their quantitative characterization will enable interventionalists to select stent lengths that span the entire PDA without encroaching on the aortic or pulmonary artery, which could cause hemodynamic interference, stent kink, and fatigue. Pulsatile PDA deformations can be used to design and evaluate devices tailored to congenital heart disease in neonates.
摘要：
■我们试图研究支架对天然动脉导管未闭(PDA)长度的影响，曲率,导管依赖性肺循环患者的搏动变形。
■使用PDA支架的患者接受了对比增强的3维计算机断层扫描，胸主动脉,和肺动脉回顾性纳入本研究.根据计算机断层扫描图像构建了支架前和支架后PDA的几何模型，和PDA波长，曲率,并量化了脉动变形。
■共纳入12例紫红色先天性心脏病患者，其中10人在PDA中接受了1个支架，2人接受了多个重叠支架。从预支架到后支架，PDA缩短了26±18%(P=.004)，平均和峰值曲率下降了60±21%和68±15%，分别(两者P<.001)。本地PDA的脉动变形变化很大，支架式PDA,和支架本身。
■支架置入后PDA的缩短和拉直是重要且实质性的，和它们的定量表征将使介入医生能够选择跨越整个PDA的支架长度，而不会侵犯主动脉或肺动脉，这可能会导致血液动力学干扰，支架扭结,和疲劳。脉冲PDA变形可用于设计和评估适合新生儿先天性心脏病的设备。
■使用PDA支架的患者接受了对比增强的3维计算机断层扫描，胸主动脉,和肺动脉回顾性纳入本研究.根据计算机断层扫描图像构建了支架前和支架后PDA的几何模型，和PDA波长，曲率,并量化了脉动变形。
■共纳入12例紫红色先天性心脏病患者，其中10人在PDA中接受了1个支架，2人接受了多个重叠支架。从预支架到后支架，PDA缩短了26±18%(P=.004)，平均和峰值曲率下降了60±21%和68±15%，分别(两者P<.001)。本地PDA的脉动变形变化很大，支架式PDA,和支架本身。
■支架置入后PDA的缩短和拉直是重要且实质性的，和它们的定量表征将使介入医生能够选择跨越整个PDA的支架长度，而不会侵犯主动脉或肺动脉，这可能会导致血液动力学干扰，支架扭结,和疲劳。脉冲PDA变形可用于设计和评估适合新生儿先天性心脏病的设备。
