使用新型抗雄激素抑制剂 ADA - 308 靶向腺癌和恩杂鲁胺耐药前列腺癌。
关键词: ARPIs enzalutamide resistance prostate cancer adenocarcinoma treatment- resistance
Mesh : Humans Male Phenylthiohydantoin / pharmacology analogs & derivatives therapeutic use Nitriles / pharmacology therapeutic use Benzamides / pharmacology therapeutic use Drug Resistance, Neoplasm / drug effects Cell Proliferation / drug effects Cell Line, Tumor Receptors, Androgen / metabolism Adenocarcinoma / drug therapy pathology Mice Animals Androgen Antagonists / pharmacology therapeutic use Xenograft Model Antitumor Assays Prostatic Neoplasms / drug therapy pathology Androgen Receptor Antagonists / pharmacology therapeutic use
来 源:
DOI:10.3892/or.2024.8791
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