Abstract:
Preterm newborns represent a population at risk of developing intestinal dysbiosis as well as being predisposed to sepsis and Necrotizing Enterocolitis. Necrotizing Enterocolitis is a condition burdened by many complications and mortality due to an alteration of the intestinal barrier, an immaturity of the immune system, and intestinal dysbiosis. Low gestational age at birth, low birth weight, and early use of antibiotics are other predisposing factors. Instead, breast milk and probiotics are protective factors in providing intestinal homeostasis and microbiome regulation. In this mini-review, we analysed the protective role of probiotics in the onset of Necrotizing Enterocolitis in preterm populations.
摘要:
早产新生儿代表处于发生肠道菌群失调以及易患败血症和坏死性小肠结肠炎的风险中的人群。坏死性小肠结肠炎是一种由肠屏障改变引起的许多并发症和死亡的疾病。免疫系统的不成熟,和肠道生态失调。出生时胎龄低,低出生体重,早期使用抗生素是其他诱发因素。相反,母乳和益生菌是提供肠道稳态和微生物组调节的保护因子。在这个小型审查中,我们分析了益生菌在早产儿坏死性小肠结肠炎发病中的保护作用.