关键词: Actionable therapeutic targets Ancillary test Cytology Effusion Molecular alterations Precision cytopathology

Mesh : Humans Precision Medicine / methods Cytodiagnosis / methods Neoplasms / pathology diagnosis genetics Biomarkers, Tumor / genetics Ascitic Fluid / pathology cytology Pleural Effusion, Malignant / pathology diagnosis

来  源:   DOI:10.1016/j.path.2024.04.008

Abstract:
Precision medicine translates through molecular assays and in minimally invasive diagnosis, evident in analyses of effusions that serve therapeutic and diagnostic purposes. This cost-effective and low-risk approach provides advantages, playing a pivotal role in late-stage oncology and frequently standing as the primary resource for cancer diagnosis and treatment pathways. This article outlines the workflow for managing serous fluid and explores how cytology effusion analysis extends beyond immunocytological diagnosis. Combined with current molecular tests it showcases the potential to be a skillful tool in precision cytopathology.
摘要:
精准医学通过分子分析和微创诊断转化,在用于治疗和诊断目的的积液分析中很明显。这种具有成本效益和低风险的方法提供了优势,在晚期肿瘤学中发挥关键作用,并经常成为癌症诊断和治疗途径的主要资源。本文概述了管理浆液的工作流程,并探讨了细胞学积液分析如何扩展到免疫细胞学诊断之外。结合当前的分子测试,它展示了成为精密细胞病理学熟练工具的潜力。
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