Abstract：
The application of bone grafting materials in bone tissue engineering is paramount for treating severe bone defects. In this comprehensive review, we explore the significance and novelty of utilizing bioactive polymers as grafts for successful bone repair. Unlike metals and ceramics, polymers offer inherent biodegradability and biocompatibility, mimicking the native extracellular matrix of bone. While these polymeric micro-nano materials may face challenges such as mechanical strength, various fabrication techniques are available to overcome these shortcomings. Our study not only investigates diverse biopolymeric materials but also illuminates innovative fabrication methods, highlighting their importance in advancing bone tissue engineering.
摘要：
骨移植材料在骨组织工程中的应用对于治疗严重的骨缺损至关重要。在这次全面审查中，我们探讨了利用生物活性聚合物作为移植物成功骨修复的意义和新颖性。不像金属和陶瓷,聚合物提供固有的生物降解性和生物相容性，模仿骨的天然细胞外基质。虽然这些聚合物微纳米材料可能面临机械强度等挑战，各种制造技术可用于克服这些缺点。我们的研究不仅调查了不同的生物聚合物材料，而且还阐明了创新的制造方法，强调它们在推进骨组织工程中的重要性。
