Abstract：
The case report by Dwyre et al. shows that vitamin B12 deficiency may be misdiagnosed as acute thrombotic thrombocytopenic purpura. Together with similar observations, this underlines that acquired vitamin B12 deficiency-besides the inherited disorder of intracellular cobalamin metabolism, cbl C disease-should be listed as a separate entity of the thrombotic microangiopathies. Commentary on: Dwyre et al. Microangiopathic thrombocytopenia caused by vitamin B12 deficiency responding to plasma exchange. Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19625.
摘要：
Dwyre等人的病例报告。表明维生素B12缺乏可能被误诊为急性血栓性血小板减少性紫癜。加上类似的观察，这强调了获得性维生素B12缺乏-除了细胞内钴胺素代谢的遗传性疾病，cblC疾病-应列为血栓性微血管病的单独实体。评论：德怀尔等人。血浆置换后维生素B12缺乏引起的微血管病性血小板减少症。BrJHaematol2024（在线印刷）。doi：10.1111/bjh.19625。
