UNASSIGNED: The six-week randomized, double-blinded, placebo-controlled trial included 31 IBS patients categorized into three groups: online yoga with probiotics (EP), online yoga with a placebo (EC), and probiotics only (P). Assessments involved physical fitness tests, subjective questionnaires (IBS-QOL, BSRS-5), and gut microbiome analysis.
METHODS: Participants self-collected stool samples and were given a set of questionnaires at baseline and after six weeks of intervention. Their symptoms were measured by changes in the gut microbiota, physical fitness and quality of life, and psychological well-being.
RESULTS: The EP group demonstrated improved cardiovascular endurance (P < 0.001) and a significant reduction in Klebsiella bacterial strains (P < 0.05). Both the EP and EC groups exhibited significantly decreased IBS-QOL scores (P < 0.001 and P < 0.05, respectively), indicating enhanced quality of life. While BSRS-5 scores decreased in both groups, the reduction was statistically insignificant.
CONCLUSIONS: Integrating online yoga, mindfulness practices, and probiotics demonstrated comprehensive benefits for IBS patients. This intervention improved physical fitness and mental well-being and positively influenced gut microbiota composition. The study highlights the potential of this multifaceted approach in managing IBS symptoms and enhancing overall health, emphasizing the relevance of the gut-muscle-brain axis in understanding and addressing IBS complexities.
BACKGROUND: Taiwanese Registry of Institutional Review Board IRBHP210009/CH11000259.
■为期六周的随机分组,双盲,安慰剂对照试验包括31名IBS患者,分为三组:益生菌在线瑜伽(EP),在线瑜伽与安慰剂(EC),只有益生菌(P)。评估包括体能测试,主观问卷(IBS-QOL,BSRS-5),和肠道微生物组分析。
方法:参与者自我收集粪便样本,并在基线和干预六周后给予一组问卷。他们的症状是通过肠道微生物群的变化来衡量的,身体素质和生活质量,和心理健康。
结果:EP组显示出改善的心血管耐力(P<0.001)和克雷伯菌菌株的显着减少(P<0.05)。EP组和EC组IBS-QOL评分均显著降低(P<0.001和P<0.05),表明生活质量提高。虽然两组的BSRS-5评分均下降,减少在统计学上无统计学意义.
结论:整合在线瑜伽,正念练习,和益生菌对IBS患者显示出综合益处。这种干预改善了身体健康和心理健康,并积极影响肠道微生物群组成。该研究强调了这种多方面方法在管理IBS症状和增强整体健康方面的潜力。强调肠-肌肉-脑轴在理解和解决IBS复杂性方面的相关性。
背景:台湾注册机构审查委员会IRBHP210009/CH11000259。