Abstract：
OBJECTIVE: This study aimed to explore the synergistic impact of online yoga, mindfulness practices, and probiotics on irritable bowel syndrome (IBS) by evaluating changes in physical fitness, mental health, and gut microbiota composition.
UNASSIGNED: The six-week randomized, double-blinded, placebo-controlled trial included 31 IBS patients categorized into three groups: online yoga with probiotics (EP), online yoga with a placebo (EC), and probiotics only (P). Assessments involved physical fitness tests, subjective questionnaires (IBS-QOL, BSRS-5), and gut microbiome analysis.
METHODS: Participants self-collected stool samples and were given a set of questionnaires at baseline and after six weeks of intervention. Their symptoms were measured by changes in the gut microbiota, physical fitness and quality of life, and psychological well-being.
RESULTS: The EP group demonstrated improved cardiovascular endurance (P < 0.001) and a significant reduction in Klebsiella bacterial strains (P < 0.05). Both the EP and EC groups exhibited significantly decreased IBS-QOL scores (P < 0.001 and P < 0.05, respectively), indicating enhanced quality of life. While BSRS-5 scores decreased in both groups, the reduction was statistically insignificant.
CONCLUSIONS: Integrating online yoga, mindfulness practices, and probiotics demonstrated comprehensive benefits for IBS patients. This intervention improved physical fitness and mental well-being and positively influenced gut microbiota composition. The study highlights the potential of this multifaceted approach in managing IBS symptoms and enhancing overall health, emphasizing the relevance of the gut-muscle-brain axis in understanding and addressing IBS complexities.
BACKGROUND: Taiwanese Registry of Institutional Review Board IRBHP210009/CH11000259.
UNASSIGNED: The six-week randomized, double-blinded, placebo-controlled trial included 31 IBS patients categorized into three groups: online yoga with probiotics (EP), online yoga with a placebo (EC), and probiotics only (P). Assessments involved physical fitness tests, subjective questionnaires (IBS-QOL, BSRS-5), and gut microbiome analysis.
METHODS: Participants self-collected stool samples and were given a set of questionnaires at baseline and after six weeks of intervention. Their symptoms were measured by changes in the gut microbiota, physical fitness and quality of life, and psychological well-being.
RESULTS: The EP group demonstrated improved cardiovascular endurance (P < 0.001) and a significant reduction in Klebsiella bacterial strains (P < 0.05). Both the EP and EC groups exhibited significantly decreased IBS-QOL scores (P < 0.001 and P < 0.05, respectively), indicating enhanced quality of life. While BSRS-5 scores decreased in both groups, the reduction was statistically insignificant.
CONCLUSIONS: Integrating online yoga, mindfulness practices, and probiotics demonstrated comprehensive benefits for IBS patients. This intervention improved physical fitness and mental well-being and positively influenced gut microbiota composition. The study highlights the potential of this multifaceted approach in managing IBS symptoms and enhancing overall health, emphasizing the relevance of the gut-muscle-brain axis in understanding and addressing IBS complexities.
BACKGROUND: Taiwanese Registry of Institutional Review Board IRBHP210009/CH11000259.
摘要：
目的：本研究旨在探讨在线瑜伽的协同影响，正念练习，和益生菌对肠易激综合征（IBS）通过评估体质变化，心理健康,和肠道菌群组成。
■为期六周的随机分组，双盲,安慰剂对照试验包括31名IBS患者，分为三组：益生菌在线瑜伽（EP），在线瑜伽与安慰剂（EC），只有益生菌（P）。评估包括体能测试，主观问卷(IBS-QOL，BSRS-5),和肠道微生物组分析。
方法：参与者自我收集粪便样本，并在基线和干预六周后给予一组问卷。他们的症状是通过肠道微生物群的变化来衡量的，身体素质和生活质量，和心理健康。
结果：EP组显示出改善的心血管耐力（P<0.001）和克雷伯菌菌株的显着减少（P<0.05）。EP组和EC组IBS-QOL评分均显著降低(P<0.001和P<0.05),表明生活质量提高。虽然两组的BSRS-5评分均下降，减少在统计学上无统计学意义.
结论：整合在线瑜伽，正念练习，和益生菌对IBS患者显示出综合益处。这种干预改善了身体健康和心理健康，并积极影响肠道微生物群组成。该研究强调了这种多方面方法在管理IBS症状和增强整体健康方面的潜力。强调肠-肌肉-脑轴在理解和解决IBS复杂性方面的相关性。
背景：台湾注册机构审查委员会IRBHP210009/CH11000259。
■为期六周的随机分组，双盲,安慰剂对照试验包括31名IBS患者，分为三组：益生菌在线瑜伽（EP），在线瑜伽与安慰剂（EC），只有益生菌（P）。评估包括体能测试，主观问卷(IBS-QOL，BSRS-5),和肠道微生物组分析。
方法：参与者自我收集粪便样本，并在基线和干预六周后给予一组问卷。他们的症状是通过肠道微生物群的变化来衡量的，身体素质和生活质量，和心理健康。
结果：EP组显示出改善的心血管耐力（P<0.001）和克雷伯菌菌株的显着减少（P<0.05）。EP组和EC组IBS-QOL评分均显著降低(P<0.001和P<0.05),表明生活质量提高。虽然两组的BSRS-5评分均下降，减少在统计学上无统计学意义.
结论：整合在线瑜伽，正念练习，和益生菌对IBS患者显示出综合益处。这种干预改善了身体健康和心理健康，并积极影响肠道微生物群组成。该研究强调了这种多方面方法在管理IBS症状和增强整体健康方面的潜力。强调肠-肌肉-脑轴在理解和解决IBS复杂性方面的相关性。
背景：台湾注册机构审查委员会IRBHP210009/CH11000259。
