PDF(Pubmed)
Abstract：
The invasive mucinous adenocarcinoma of the lungs (LIMA) is an uncommon histological subtype of the mucinous adenocarcinoma. In this article, we present the case of a patient with a very high cardiovascular risk profile, diagnosed with LIMA, pericardial tamponade due to secondary dissemination, and pulmonary embolism, whose management rouses many challenges. Despite receiving the correct anticoagulant and antiaggregant therapy, our patient developed repeated acute major cardiovascular events leading to a fatal outcome. To gather additional information on LIMA and the above cluster of pathologies, we performed the first research of the international medical literature for scientific articles published in the last eight years on PubMed, ResearchGate, Clarivate, and Google Scholar. As the first literature research failed to identify any case similar to our patient, we performed a second study of the same databases for subjects with lung adenocarcinoma instead of LIMA and the same comorbidities, and we found 10 cases. LIMA is a less frequent type of adenocarcinoma, with polymorphic radiologic appearances on the chest computed tomography, frequently mimicking pneumonia, and thus delaying the diagnosis and therapy. It has a worse prognosis and higher mortality than the common adenocarcinoma, but information on its secondary dissemination and complications is still required.
摘要：
肺浸润性粘液腺癌（LIMA）是粘液腺癌的一种罕见组织学亚型。在这篇文章中,我们介绍了一个心血管风险非常高的患者，诊断为LIMA,由于二次传播引起的心包填塞，和肺栓塞,其管理引发了许多挑战。尽管接受了正确的抗凝和抗凝治疗，我们的患者出现了反复的急性主要心血管事件,导致了致命的结局.为了收集有关LIMA和上述病理簇的其他信息，我们对过去八年在PubMed上发表的科学文章进行了国际医学文献的第一项研究，ResearchGate,Clarivate,谷歌学者。由于第一项文献研究未能确定任何与我们患者相似的病例，我们对相同的数据库进行了第二次研究，研究对象的肺腺癌而不是LIMA和相同的合并症，我们发现了10个案子.LIMA是一种不太常见的腺癌，在胸部计算机断层扫描上有多态放射学表现，经常模仿肺炎，从而延误了诊断和治疗.与普通腺癌相比，预后差，死亡率高，但仍需要有关其二次传播和并发症的信息。
