PDF(Pubmed)
Abstract：
The objective of this study is to explore the associations between obesity, body composition, and the self-reported risk of obstructive sleep apnea (OSA) and to examine whether the risk of OSA is related to metabolic abnormalities in children and adolescents aged 6-17 years. Utilizing data from the 2022 to 2023 Beijing Children and Adolescents Health Cohort baseline survey, 5000 school-aged participants were analyzed. OSA risk was assessed via the Pediatric Sleep Questionnaire, with anthropometric and body composition measurements taken. Metabolic markers included blood pressure, lipid levels, blood glucose, and uric acid. Associations were analyzed using logistic regression and generalized linear models. Results showed that 88.6% were low-risk and 11.4% were high-risk for OSA. Overweight (aOR 1.53, 95% CI 1.22-1.92), obesity (aOR 1.94, 95% CI 1.57-2.40), and abdominal obesity (aOR 1.59, 95% CI 1.31-1.93) significantly increased OSA risk. High fat mass was a critical factor, while muscle mass was not, especially in those who were overweight and obese. Associations of OSA risk with metabolic abnormalities were non-significant after adjusting for BMI. Our research highlights the significant associations of obesity and body composition with OSA risk, with child BMI influencing the relationship between OSA and metabolic abnormalities. Future research should explore causative relationships and the enduring impacts of OSA on metabolic health in children.
摘要：
这项研究的目的是探讨肥胖之间的关系，身体成分,和自我报告的阻塞性睡眠呼吸暂停（OSA）的风险，并检查OSA的风险是否与6-17岁儿童和青少年的代谢异常有关。利用2022-2023年北京儿童青少年健康队列基线调查数据，对5000名学龄参与者进行了分析。OSA风险通过儿科睡眠问卷进行评估，进行人体测量和身体成分测量。代谢标志物包括血压,脂质水平，血糖，和尿酸。使用逻辑回归和广义线性模型分析关联。结果显示，OSA的低风险为88.6%，高风险为11.4%。超重（AOR1.53，95%CI1.22-1.92），肥胖（aOR1.94，95%CI1.57-2.40），和腹型肥胖(aOR1.59,95%CI1.31-1.93)显著增加OSA风险。高脂肪量是一个关键因素，而肌肉质量不是，尤其是那些超重和肥胖的人。调整BMI后，OSA风险与代谢异常的相关性无统计学意义。我们的研究强调了肥胖和身体成分与OSA风险的显著关联，儿童BMI影响OSA与代谢异常的关系。未来的研究应该探讨OSA对儿童代谢健康的因果关系和持久影响。
