PDF(Pubmed)
Abstract：
Cotton is used for the production of textiles, hygiene and cosmetic materials. During cultivation and technological processes, various types of substances (surfactants, softeners, lubricants, etc.) penetrate cotton, which can have a harmful effect on both the human body and the environment. The aim of this study was to analyze selected cotton products in order to identify the substances contained and to describe the potential possibilities of inducing textile contact dermatitis (CD). The impact of the identified compounds on the aquatic environment was also taken into account. Nine samples of cotton clothing and seven samples of cotton pads from various manufacturers were tested. Samples after extraction using the FUSLE (Focused Ultrasonic Liquid Extraction) technique were analyzed with GC/MS. Qualitative analysis was based on comparing mass spectra with library spectra using the following mass spectra deconvolution programs: MassHunter (Agilent), AMDIS (NIST), and PARADISE (University of Copenhagen). The parameter confirming the identification of the substance was the retention index. Through the non-target screening process, a total of 36 substances were identified, with an average AMDIS match factor of approximately 900 (\"excellent match\"). Analyzing the properties of the identified compounds, it can be concluded that most of them have potential properties that can cause CD, also due to the relatively high content in samples. This applies primarily to long-chain alkanes (C25-C31), saturated fatty acids, fatty alcohols (e.g., oleyl alcohol), and fatty acid amides (e.g., oleamide). However, there are not many reports describing cases of cotton CD. Information on the identified groups of compounds may be helpful in the case of unexplained sources of sensitization when the skin comes into contact with cotton materials. Some of the identified compounds are also classified as dangerous for aquatic organisms, especially if they can be released during laundering.
摘要：
棉花是用来生产纺织品的,卫生和化妆品材料。在种植和技术过程中，各种类型的物质(表面活性剂，软化剂，润滑剂等。)渗透棉花，会对人体和环境产生有害影响。这项研究的目的是分析选定的棉制品，以确定所含的物质并描述诱发纺织品接触性皮炎（CD）的潜在可能性。还考虑了所确定的化合物对水生环境的影响。测试了来自各个制造商的9个棉衣样品和7个棉垫样品。使用FUSLE（聚焦超声液体提取）技术提取后的样品用GC/MS进行分析。定性分析基于使用以下质谱反卷积程序将质谱与库光谱进行比较：MassHunter（Agilent），AMDIS(NIST),和天堂（哥本哈根大学）。确认物质的鉴定的参数是保留指数。通过非靶标筛选过程,共鉴定出36种物质，平均AMDIS匹配系数约为900（“优秀匹配”）。分析已鉴定化合物的性质，可以得出结论，它们中的大多数都具有可能导致CD的潜在特性，也是由于样品中含量相对较高。这主要适用于长链烷烃（C25-C31），饱和脂肪酸，脂肪醇(例如，油醇)，和脂肪酸酰胺(例如，油酰胺）。然而,描述棉花CD病例的报道并不多。当皮肤与棉材料接触时，有关已识别化合物组的信息可能对无法解释的致敏来源的情况有所帮助。一些已确定的化合物也被归类为对水生生物有危险，特别是如果它们可以在清洗过程中释放。
