PDF(Pubmed)
Abstract：
Fracture risk is increased in men with prostate cancer (PCa) receiving Androgen Deprivation Therapy (ADT). However, routine assessment of fracture risk is often not systematically applied. We aimed to establish a comprehensive care pathway for fracture prevention in men with PCa starting ADT. Therefore, a multidisciplinary working group designed and implemented a care pathway using the \'Knowledge to Action\' framework, based on current Dutch guidelines for PCa, osteoporosis and fracture prevention, and an extensive literature review of other guidelines. The pathway was developed according to a five-step clinical approach including case finding, fracture risk assessment based on risk factors, bone mineral density test, vertebral fracture assessment, differential diagnosis, treatment, and annual follow-up. Our fracture prevention care pathway for patients with PCa at the time of ADT initiation was designed to promote a patient-centered, multidisciplinary approach to facilitate the implementation of early fracture prevention measures.
摘要：
接受雄激素剥夺治疗（ADT）的前列腺癌（PCa）男性骨折风险增加。然而,骨折风险的常规评估通常没有系统的应用。我们旨在为开始ADT的PCa男性骨折预防建立全面的护理途径。因此,一个多学科工作组使用“知识到行动”框架设计和实施了一条护理途径，根据荷兰现行的PCa指南，骨质疏松症和骨折预防，以及对其他指南的广泛文献综述。该途径是根据包括病例发现在内的五步临床方法开发的，基于风险因素的骨折风险评估，骨密度测试，椎体骨折评估，鉴别诊断,治疗,年度随访。我们在ADT开始时针对PCa患者的骨折预防护理路径旨在促进以患者为中心，多学科方法促进早期骨折预防措施的实施。
