piRNA 生物发生的遗传性缺陷导致转座子去抑制 ,精子发生受损 ,和人类男性不育。
Mesh : Male Humans Spermatogenesis / genetics Infertility, Male / genetics metabolism pathology RNA, Small Interfering / metabolism genetics DNA Transposable Elements / genetics Animals Testis / metabolism Mice Adult Gene Silencing Mice, Knockout Argonaute Proteins / metabolism genetics Long Interspersed Nucleotide Elements / genetics Spermatogonia / metabolism DEAD-box RNA Helicases / genetics metabolism Piwi-Interacting RNA
来 源:
DOI:10.1038/s41467-024-50930-9
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