PDF(Pubmed)
Abstract：
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric condition prevalent in both children and adults. With growing awareness of the importance of the preconception period in health, it is essential to understand whether preconception parental mental health and related factors are related to onset of offspring ADHD. This protocol presents the methodology for undertaking a systematic review to investigate associations between parental mental health and/or psychotropic use during the preconception years and offspring ADHD.
METHODS: Peer-reviewed literature will be identified by searching relevant electronic databases including Medline complete, Embase, PsycINFO and CINAHL; reference lists of eligible articles will be hand searched and grey literature considered. Eligible study designs include population-based and/or clinically based cohort or case-control studies. The primary exposure and outcome of interest is parental history of mental health conditions in the preconception period and offspring ADHD, respectively (ie, according to semistructured interviews/confirmed diagnosis by a relevant health professional or screening instruments). Critical appraisal will be undertaken. A descriptive synthesis will be presented including characteristics of the included studies, critical appraisal scores and a summary of main findings (eg, presented in tables, text and figures). A meta-analysis will be conducted, if possible, and statistical techniques will be employed if heterogeneity is detected.
BACKGROUND: Ethical permissions are not required for this systematic review since the study will only use published data. Findings from this systematic review will be published in a peer-reviewed scientific journal/presented at national and international conferences relevant to the field.
UNASSIGNED: CRD42023460379.
METHODS: Peer-reviewed literature will be identified by searching relevant electronic databases including Medline complete, Embase, PsycINFO and CINAHL; reference lists of eligible articles will be hand searched and grey literature considered. Eligible study designs include population-based and/or clinically based cohort or case-control studies. The primary exposure and outcome of interest is parental history of mental health conditions in the preconception period and offspring ADHD, respectively (ie, according to semistructured interviews/confirmed diagnosis by a relevant health professional or screening instruments). Critical appraisal will be undertaken. A descriptive synthesis will be presented including characteristics of the included studies, critical appraisal scores and a summary of main findings (eg, presented in tables, text and figures). A meta-analysis will be conducted, if possible, and statistical techniques will be employed if heterogeneity is detected.
BACKGROUND: Ethical permissions are not required for this systematic review since the study will only use published data. Findings from this systematic review will be published in a peer-reviewed scientific journal/presented at national and international conferences relevant to the field.
UNASSIGNED: CRD42023460379.
摘要：
背景：注意缺陷多动障碍（ADHD）是一种普遍存在于儿童和成人中的神经精神疾病。随着人们越来越意识到孕前时期在健康中的重要性，了解孕前父母的心理健康和相关因素是否与后代ADHD的发病有关至关重要。该协议提供了进行系统审查的方法，以调查孕前时期父母心理健康和/或精神药物使用与后代ADHD之间的关联。
方法：同行评审的文献将通过搜索相关电子数据库来识别，包括Medlinecomplete，Embase,PsycINFO和CINAHL；将手工搜索合格文章的参考列表，并考虑灰色文献。合格的研究设计包括基于人群和/或基于临床的队列或病例对照研究。主要的暴露和关注的结果是父母在孕前时期的心理健康状况史和后代ADHD，分别(即，根据相关健康专业人员或筛查工具的半结构化访谈/确认诊断)。将进行严格的评估。将提供描述性综合，包括所包括研究的特征，关键评估分数和主要发现总结(例如，在表格中呈现，文字和数字)。将进行荟萃分析，如果可能,如果检测到异质性，将采用统计技术。
背景：本系统综述不需要伦理许可，因为本研究将仅使用已发布的数据。本系统评价的结果将发表在同行评审的科学期刊上，并在与该领域相关的国家和国际会议上发表。
■CRD42023460379。
方法：同行评审的文献将通过搜索相关电子数据库来识别，包括Medlinecomplete，Embase,PsycINFO和CINAHL；将手工搜索合格文章的参考列表，并考虑灰色文献。合格的研究设计包括基于人群和/或基于临床的队列或病例对照研究。主要的暴露和关注的结果是父母在孕前时期的心理健康状况史和后代ADHD，分别(即，根据相关健康专业人员或筛查工具的半结构化访谈/确认诊断)。将进行严格的评估。将提供描述性综合，包括所包括研究的特征，关键评估分数和主要发现总结(例如，在表格中呈现，文字和数字)。将进行荟萃分析，如果可能,如果检测到异质性，将采用统计技术。
背景：本系统综述不需要伦理许可，因为本研究将仅使用已发布的数据。本系统评价的结果将发表在同行评审的科学期刊上，并在与该领域相关的国家和国际会议上发表。
■CRD42023460379。
