PDF(Pubmed)
Abstract：
The use of integrative Korean medicine treatment (IKMT) for patients with knee osteoarthritis (OA) has been reported previously; however, to date, no studies have investigated the long-term prognosis of these patients following IKMT for primary knee OA. We aimed to examine the long-term effects of IKMT in patients diagnosed with primary knee OA and receiving IKMT during hospitalization. This retrospective observational study, complemented by a follow-up survey, included patients with primary knee OA who received IKMT during hospitalization across 7 Korean medicine hospitals. The primary outcome was the Numerical Rating Scale knee-pain score, whereas the secondary outcomes were the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), EuroQol-5 dimension-5 level questionnaire (EQ-5D-5L), and Patient Global Impression of Change scores. Patients were evaluated at admission, discharge, and during follow-up. Of the 180 included patients, 81 responded to the survey. Compared with the corresponding values at admission, the Numerical Rating Scale score decreased by 2.44 (2.08-2.81) points at discharge and 1.89 (1.5-2.26) points at follow-up. Additionally, compared with their scores at admission, the WOMAC score decreased by 17.20 (13.68-20.71) points at discharge and 25.74 (22.22-29.26) points at follow-up, whereas the EuroQol-5 dimension-5 level questionnaire score improved by -0.15 (-0.18 to -0.12) points at discharge and -0.12 (-0.15 to -0.09) points at follow-up. The patients expressed high satisfaction with pharmacopuncture (65.4%), acupuncture (54.03%), physical therapy (35.8%), and herbal medicine (34.6%). Regarding Patient Global Impression of Change, 96.30% of the patients reported improvement. IKMT was effective in improving pain, functional disability, and quality of life in patients with primary knee OA. Its effects were maintained throughout the long-term follow-up period, and physical functions continuously improved.
摘要：
以前曾报道过对膝骨关节炎（OA）患者使用韩国综合药物治疗（IKMT）；然而，到目前为止,尚无研究调查IKMT治疗原发性膝关节OA后这些患者的长期预后.我们旨在研究IKMT对诊断为原发性膝关节OA并在住院期间接受IKMT的患者的长期影响。这项回顾性观察研究，辅之以后续调查，纳入7家韩国医药医院住院期间接受IKMT治疗的原发性膝关节OA患者。主要结果是数值评定量表膝关节疼痛评分，而次要结局是西安大略省和麦克马斯特大学骨关节炎指数（WOMAC），EuroQol-5维度-5级问卷(EQ-5D-5L)，和患者对变化的整体印象评分。患者在入院时进行评估，放电,在后续行动中。在180名患者中，81回答了调查。与入院时的相应值相比，出院时数值评定量表评分下降2.44(2.08-2.81)分,随访时下降1.89(1.5-2.26)分。此外,与入学时的分数相比，出院时WOMAC评分下降17.20(13.68-20.71)分,随访时下降25.74(22.22-29.26)分,而EuroQol-5维度-5级问卷评分在出院时提高了-0.15(-0.18~-0.12)分,在随访时提高了-0.12(-0.15~-0.09)分.患者对药物穿刺表示高度满意（65.4%），针灸(54.03%)，物理治疗(35.8%)，和草药(34.6%)。关于患者对变化的全球印象，96.30%的患者报告改善。IKMT能有效改善疼痛,功能性残疾，原发性膝关节OA患者的生活质量。其效果在整个长期随访期间保持不变，身体机能不断提高。
