Abstract：
UNASSIGNED: The aim of this study is to investigate the correlation between the triglyceride-glucose-body mass index (TyG-BMI) and the characteristics of various carotid plaques in middle-aged and elderly patients with acute myocardial infarction (AMI).
UNASSIGNED: A retrospective study was conducted on 380 patients with AMI hospitalized in the Cardiology Department of Kaifeng Central Hospital. Based on carotid ultrasound results, patients were divided into the following two groups: the stable plaque group and the unstable plaque group. Additionally, a control group comprising 380 healthy individuals visiting the hospital\'s physical examination center during the same timeframe was established. Fasting venous blood samples were collected from all participants to measure blood glucose and triglyceride. The baseline TyG-BMI index was calculated using the formula Ln [fasting triglyceride (mg/dL)×fasting blood glucose (mg/dL)/2]×BMI. The correlation between different plaque groups and the TyG-BMI index was analyzed.
UNASSIGNED: The TyG-BMI index was significantly higher in the unstable plaque group compared to the stable plaque group, with values of 252.81±29.99 and 201.92±28.72, respectively (P = 0.034). Spearman\'s correlation analysis showed a positive correlation between the instability of carotid plaques and the TyG-BMI index in patients with AMI (r = 0.521, P = 0.003). Logistic regression analysis indicated that the TyG-BMI index was an important risk factor for unstable carotid plaques in patients with AMI (OR = 2.691, 95% CI: 1.169-4.123).
UNASSIGNED: The findings of this study suggest that an elevated TyG-BMI index significantly increases the risk of unstable carotid plaques in patients with AMI, making it an important risk factor for carotid plaque instability.
UNASSIGNED: A retrospective study was conducted on 380 patients with AMI hospitalized in the Cardiology Department of Kaifeng Central Hospital. Based on carotid ultrasound results, patients were divided into the following two groups: the stable plaque group and the unstable plaque group. Additionally, a control group comprising 380 healthy individuals visiting the hospital\'s physical examination center during the same timeframe was established. Fasting venous blood samples were collected from all participants to measure blood glucose and triglyceride. The baseline TyG-BMI index was calculated using the formula Ln [fasting triglyceride (mg/dL)×fasting blood glucose (mg/dL)/2]×BMI. The correlation between different plaque groups and the TyG-BMI index was analyzed.
UNASSIGNED: The TyG-BMI index was significantly higher in the unstable plaque group compared to the stable plaque group, with values of 252.81±29.99 and 201.92±28.72, respectively (P = 0.034). Spearman\'s correlation analysis showed a positive correlation between the instability of carotid plaques and the TyG-BMI index in patients with AMI (r = 0.521, P = 0.003). Logistic regression analysis indicated that the TyG-BMI index was an important risk factor for unstable carotid plaques in patients with AMI (OR = 2.691, 95% CI: 1.169-4.123).
UNASSIGNED: The findings of this study suggest that an elevated TyG-BMI index significantly increases the risk of unstable carotid plaques in patients with AMI, making it an important risk factor for carotid plaque instability.
摘要：
■本研究的目的是探讨中老年急性心肌梗死（AMI）患者的甘油三酯-葡萄糖-体重指数（TyG-BMI）与各种颈动脉斑块特征之间的相关性。
■对开封市中心医院心内科住院的380例AMI患者进行了回顾性研究。根据颈动脉超声检查结果,患者分为稳定斑块组和不稳定斑块组。此外,建立了一个由380名健康个体组成的对照组，这些个体在同一时间段内访问了医院的体检中心。从所有参与者收集空腹静脉血样本以测量血糖和甘油三酯。使用公式Ln[空腹甘油三酯(mg/dL)×空腹血糖(mg/dL)/2]×BMI计算基线TyG-BMI指数。分析不同斑块组与TyG-BMI指数的相关性。
■不稳定斑块组的TyG-BMI指数明显高于稳定斑块组,值分别为252.81±29.99和201.92±28.72(P=0.034)。Spearman相关分析显示,AMI患者颈动脉斑块不稳定性与TyG-BMI指数呈正相关(r=0.521,P=0.003)。Logistic回归分析显示,TyG-BMI指数是AMI患者颈动脉不稳定斑块的重要危险因素(OR=2.691,95%CI:1.169~4.123)。
■这项研究的结果表明，升高的TyG-BMI指数会显著增加AMI患者颈动脉不稳定斑块的风险，使其成为颈动脉斑块不稳定的重要危险因素。
■对开封市中心医院心内科住院的380例AMI患者进行了回顾性研究。根据颈动脉超声检查结果,患者分为稳定斑块组和不稳定斑块组。此外,建立了一个由380名健康个体组成的对照组，这些个体在同一时间段内访问了医院的体检中心。从所有参与者收集空腹静脉血样本以测量血糖和甘油三酯。使用公式Ln[空腹甘油三酯(mg/dL)×空腹血糖(mg/dL)/2]×BMI计算基线TyG-BMI指数。分析不同斑块组与TyG-BMI指数的相关性。
■不稳定斑块组的TyG-BMI指数明显高于稳定斑块组,值分别为252.81±29.99和201.92±28.72(P=0.034)。Spearman相关分析显示,AMI患者颈动脉斑块不稳定性与TyG-BMI指数呈正相关(r=0.521,P=0.003)。Logistic回归分析显示,TyG-BMI指数是AMI患者颈动脉不稳定斑块的重要危险因素(OR=2.691,95%CI:1.169~4.123)。
■这项研究的结果表明，升高的TyG-BMI指数会显著增加AMI患者颈动脉不稳定斑块的风险，使其成为颈动脉斑块不稳定的重要危险因素。
