Abstract：
Wounds are the common fates in various microbial infections and physical damages including accidents, surgery, and burns. In response, a healthy body with a potent immune system heals that particular site within optimal time by following the coagulation, inflammation, proliferation, and remodeling phenomenon. However, certain malfunctions in the body due to various diseases particularly diabetes and other physiological factors like age, stress, etc., prolong the process of wound healing through various mechanisms including the Akt, Polyol, and Hexosamine pathways. The current review thoroughly explains the wound types, normal wound healing mechanisms, and the immune system\'s role. Moreover, the mechanistic role of diabetes is also elaborated comprehensively.
摘要：
创伤是各种微生物感染和包括事故在内的身体损害的常见命运，手术,和烧伤。作为回应,一个具有强大免疫系统的健康身体通过凝血在最佳时间内治愈特定部位，炎症,扩散,和重塑现象。然而,由于各种疾病，特别是糖尿病和其他生理因素，如年龄，压力，等。,通过各种机制延长伤口愈合的过程，包括Akt，多元醇,和己胺途径。当前的评论彻底解释了伤口类型，正常的伤口愈合机制，和免疫系统的作用。此外，对糖尿病的机制作用也进行了全面阐述。
