PDF(Pubmed)
Abstract：
BACKGROUND: Takayasu arteritis (TA) is a chronic inflammatory disease of unknown etiology characterized by a large vessel vasculitis involving the aorta and its branches. Myocardial involvement is extremely unusual in TA and is mostly in the form of myocarditis, ventricular hypertrophy, and ventricular dysfunction secondary to coronary ischemia. Submitral aneurysms have been reported in TA and has been attributed to the chronic inflammatory process in TA.
METHODS: We report a novel instance of left ventricular apical aneurysm in a 37-year-old lady with TA and normal epicardial coronaries. She was diagnosed with a left ventricular apical aneurysm, moderate aortic regurgitation, and moderate pericardial effusion. The coronary arteries were normal. The patient had concomitant chronic active Epstein-Barr virus infection complicating patient outcome.
CONCLUSIONS: Left ventricular apical aneurysm with normal epicardial coronaries is a rare cause of heart failure in Takayasu arteritis. Concomitant chronic active Epstein-Barr virus infection can potentially accentuate the inflammatory process in Takayasu arteritis and complicate management and patient outcomes.
METHODS: We report a novel instance of left ventricular apical aneurysm in a 37-year-old lady with TA and normal epicardial coronaries. She was diagnosed with a left ventricular apical aneurysm, moderate aortic regurgitation, and moderate pericardial effusion. The coronary arteries were normal. The patient had concomitant chronic active Epstein-Barr virus infection complicating patient outcome.
CONCLUSIONS: Left ventricular apical aneurysm with normal epicardial coronaries is a rare cause of heart failure in Takayasu arteritis. Concomitant chronic active Epstein-Barr virus infection can potentially accentuate the inflammatory process in Takayasu arteritis and complicate management and patient outcomes.
摘要：
背景：大动脉炎（TA）是一种病因不明的慢性炎症性疾病，其特征是累及主动脉及其分支的大血管血管炎。TA中的心肌受累极为罕见，主要以心肌炎的形式出现，心室肥大,和冠状动脉缺血继发的心室功能障碍。已经在TA中报道了二尖瓣下动脉瘤,并且已经归因于TA中的慢性炎症过程。
方法：我们报告了一个新的病例，该病例是一名37岁的女性，患有TA和正常的心外膜冠状动脉。她被诊断出患有左心室心尖动脉瘤,中度主动脉瓣反流,中度心包积液。冠状动脉正常。患者患有慢性活动性EB病毒感染，使患者预后复杂化。
结论：心外膜冠状动脉正常的左心室心尖部动脉瘤是大动脉炎心力衰竭的罕见原因。伴随的慢性活动性EB病毒感染可能会加剧大动脉炎的炎症过程，并使治疗和患者预后复杂化。
方法：我们报告了一个新的病例，该病例是一名37岁的女性，患有TA和正常的心外膜冠状动脉。她被诊断出患有左心室心尖动脉瘤,中度主动脉瓣反流,中度心包积液。冠状动脉正常。患者患有慢性活动性EB病毒感染，使患者预后复杂化。
结论：心外膜冠状动脉正常的左心室心尖部动脉瘤是大动脉炎心力衰竭的罕见原因。伴随的慢性活动性EB病毒感染可能会加剧大动脉炎的炎症过程，并使治疗和患者预后复杂化。
