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Abstract：
In the context of advanced nanomaterials research, nanogels (NGs) have recently gained broad attention for their versatility and promising biomedical applications. To date, a significant number of NGs have been developed to meet the growing demands in various fields of biomedical research. Summarizing preparation methods, physicochemical and biological properties, and recent applications of NGs may be useful to help explore new directions for their development. This article presents a comprehensive overview of the latest NG synthesis methodologies, highlighting advances in formulation with different types of hydrophilic or amphiphilic polymers. It also underlines recent biomedical applications of NGs in drug delivery and imaging, with a short section dedicated to biosafety considerations of these innovative nanomaterials. In conclusion, this article summarizes recent innovations in NG synthesis and their numerous applications, highlighting their considerable potential in the biomedical field.
摘要：
在先进纳米材料研究的背景下，纳米凝胶（NGs）最近因其多功能性和有前途的生物医学应用而受到广泛关注。迄今为止,已经开发了大量的NG，以满足生物医学研究各个领域日益增长的需求。总结制备方法，物理化学和生物学特性，NGs的最新应用可能有助于探索其发展的新方向。本文全面介绍了最新的NG合成方法，突出了不同类型亲水或两亲性聚合物配方的进展。它还强调了NG在药物输送和成像方面的最新生物医学应用，一小段致力于这些创新纳米材料的生物安全考虑。总之,本文总结了NG合成的最新创新及其众多应用，突出了他们在生物医学领域的巨大潜力。
