Abstract：
Due to the high mortality rate of TS, effective guidance for its diagnosis and treatment is essential. The diagnostic criteria introduced by the JTA in 2012, along with the Burch-Wartofsky Point Scale, constitute valuable tools for the diagnosis of TS. In 2016, Guidelines on the management of TS were produced by the JTA and the JES. Recently, a prospective multicenter register-based study compared the prognosis and outcome of 110 new-onset TS patients with the results of previous comparable studies and evaluated the efficacy of the Guidelines. The study revealed higher APACHE II scores and significant correlations between lower BMI, post-resuscitation shock, and fever with outcomes and, overall, improved TS prognosis. Most patients in the study received methimazole and potassium iodide, the timely administration of which was linked to lower fatality rates. Adherence to treatment guidelines correlates with lower mortality rates, emphasizing the importance of experienced multidisciplinary teams in ICU settings and the necessity for periodic review of the guidelines to enhance therapeutic approaches and reduce mortality.
摘要：
由于TS的高死亡率，有效指导其诊断和治疗至关重要。JTA在2012年引入的诊断标准，以及Burch-WartofskyPointScale，构成TS诊断的有价值的工具。2016年，JTA和JES制定了TS管理指南。最近,一项基于多中心登记的前瞻性研究将110例新发TS患者的预后和结局与之前的可比研究结果进行了比较,并评估了指南的疗效.研究表明，较高的APACHEII评分与较低的BMI之间存在显着相关性，复苏后休克,和发烧的结果，总的来说,改善TS预后。研究中的大多数患者接受了甲氧咪唑和碘化钾，及时的管理与较低的死亡率有关。坚持治疗指南与较低的死亡率相关，强调ICU环境中经验丰富的多学科团队的重要性，以及定期审查指南以加强治疗方法和降低死亡率的必要性。
