PDF(Pubmed)
Abstract：
Immune reconstitution inflammatory syndrome (IRIS) is a potentially life-threatening phenomenon associated with the initiation of antiretroviral therapy in patients with acquired immunodeficiency syndrome due to a human immunodeficiency virus (HIV) infection. It is thought to be an exaggerated inflammatory response to an existing pathogen or even its antigen. We present a case of IRIS due to a non-tuberculous mycobacteria infection in a young patient with HIV infection who was recently started on therapy. This case highlights the challenges of making such a diagnosis and the importance of multidisciplinary team discussions with pulmonary and infectious diseases for optimal management of these patients.
摘要：
免疫重建炎症综合征（IRIS）是一种潜在的威胁生命的现象，与人类免疫缺陷病毒（HIV）感染导致的获得性免疫缺陷综合征患者开始抗逆转录病毒治疗有关。它被认为是对现有病原体或甚至其抗原的夸大的炎症反应。我们在最近开始接受治疗的年轻HIV感染患者中介绍了由于非结核分枝杆菌感染引起的IRIS病例。这个案例强调了做出这样的诊断的挑战以及与肺部和感染性疾病的多学科团队讨论对这些患者的最佳管理的重要性。
