UNASSIGNED: Dermoscopic findings in 32 biopsy-proven BCCs and RCM findings in 10 biopsy-proven BCCs developed in seven XP patients were reviewed.
UNASSIGNED: Of 32 BCCs, 28 were pigmented. On dermoscopy, BCCs exhibited multiple grey-blue globules/dots (81, 3%), short-fine telangiectasias/fine arborising vessels (65, 6%), multiple grey-blue ovoid nests (53, 1%), white structures (white-red structureless areas/shiny white areas/lines/strands) (56, 3%), arborising vessels (37, 5%), brown nests/globules/dots (28, 1%), spoke-wheel structures (9, 4%), leaf-like areas (9, 4%), ulceration (28, 1%), peripheral network (21, 9%), and multiple aggregated yellow-white globules (3, 1%). In 10 lesions in which further imaging with RCM was performed, RCM findings differentiated BCC from other tumours, including primary melanoma.
UNASSIGNED: Although the dominancy of pigmented structures may imitate melanoma clinically, dermoscopy is a valuable tool in the early diagnosis of BCCs in patients with XP. For suspicious lesions, RCM can help in differentiating pigmented BCC from primary melanoma.
■对7例XP患者中32例活检证实的BCC的皮肤镜检查结果和10例活检证实的BCC的RCM结果进行了回顾。
■在32个BCC中,28人有色素。在皮肤镜上,BCC表现出多个灰蓝色小球/点(81,3%),短细毛细血管扩张/细血管(65,6%),多个灰蓝色卵形巢(53,1%),白色结构(白色-红色无结构区域/闪亮的白色区域/线/线)(56,3%),树胶船(37%,5%),棕色巢/球/点(28,1%),轮辐结构(9%,4%),叶状面积(9%,4%),溃疡(28,1%),外围网络(21,9%),和多个聚集的黄白色小球(3,1%)。在进行了RCM进一步成像的10个病变中,RCM发现将BCC与其他肿瘤区分开来,包括原发性黑色素瘤.
■尽管色素结构的优势可能在临床上模仿黑色素瘤,皮肤镜检查是XP患者早期诊断BCCs的有价值的工具。对于可疑病变,RCM可以帮助区分色素性BCC与原发性黑色素瘤。