PDF(Pubmed)
Abstract：
Extranodal non-Hodgkin\'s lymphoma (NHL) afflicting the head and neck region is rare, accounting for only about 5%. Diffuse large B-cell lymphoma (DLBCL) is the most common type of NHL affecting the oral cavity. Due to its variable clinical presentation and non-pathognomic course, it can be easily misdiagnosed with overlapping characteristics to common oral pathologies. In the present case, the authors report an unusual presentation of DLBCL and highlight the significant diagnostic challenge encountered by the clinician. In our case, osteonecrosis of the maxilla with soft tissue swelling misleads the diagnosis of chronic osteomyelitis. However, further, work-up was pursued, and the patient was managed successfully with chemotherapy and is currently disease-free for the past 1 year. An accurate clinico-radiological diagnosis with histopathological confirmation is emphasized to deliver a potentially curative treatment in a timely manner.
摘要：
影响头颈部的结外非霍奇金淋巴瘤（NHL）很少见，只占5%左右。弥漫性大B细胞淋巴瘤（DLBCL）是影响口腔的最常见类型的NHL。由于其可变的临床表现和非病理过程，它很容易被误诊，具有与常见口腔疾病重叠的特征。在目前的情况下,作者报告了DLBCL的异常表现,并强调了临床医生遇到的重大诊断挑战.在我们的案例中,上颌骨坏死伴软组织肿胀会误导慢性骨髓炎的诊断。然而,进一步,继续努力，该患者通过化疗成功治疗,目前在过去1年内无病.强调具有组织病理学确认的准确的临床放射学诊断，以及时提供潜在的治愈性治疗。
