关键词: coxsackie B virus embolic stroke viral myocarditis

来  源:   DOI:10.1097/MS9.0000000000002069   PDF(Pubmed)

Abstract:
UNASSIGNED: Stroke, a global health concern, often results from embolic events of cardiac origin. Coxsackie B virus (CBV) myocarditis, a common cause of viral heart infections, can lead to cardiac thrombi formation, subsequently causing devastating complications such as embolic stroke. The authors present a rare case of a 26-year-old male who experienced an embolic stroke following CBV myocarditis and cardiomyopathy.
UNASSIGNED: The patient exhibited left-sided weakness, facial droop, and respiratory distress. Laboratory findings indicated leukocytosis, hyponatremia, and elevated troponin I. Imaging revealed an acute right basal ganglia infarct and multifocal pulmonary embolism. The diagnosis involved positive CBV serology, severely reduced left ventricular function, and a large apical thrombus.
UNASSIGNED: Cardioembolic strokes, often attributable to atrial fibrillation, can also result from intracardiac thrombosis associated with myocarditis. CBV, implicated in up to 40% of acute myocarditis cases, binds to cardiac myocytes, triggering inflammation and potential thrombus formation. Myocarditis-induced hypercoagulability increases the risk of thromboembolic events, complicating the clinical course.
UNASSIGNED: CBV myocarditis poses a risk of heart failure, cardiomyopathy, and thromboembolic complications such as embolic stroke. Vigilant monitoring for complications and prompt management is crucial, as primary disease treatment remains primarily supportive. This case highlights the need for increased awareness and further studies to understand the intricate relationship between viral myocarditis and embolic strokes.
摘要:
中风,全球健康问题,通常是由心脏起源的栓塞事件引起的。柯萨奇B型病毒(CBV)心肌炎,病毒性心脏病感染的常见原因,会导致心脏血栓形成,随后导致破坏性并发症,如栓塞性中风。作者介绍了一例罕见的26岁男性病例,该病例在CBV心肌炎和心肌病后发生了栓塞性中风。
患者出现左侧无力,面部下垂,和呼吸窘迫。实验室检查结果提示白细胞增多,低钠血症,和肌钙蛋白I升高。影像学显示急性右基底节梗死和多灶性肺栓塞。诊断涉及CBV血清学阳性,左心室功能严重下降,和一个大的心尖血栓.
心源性卒中,通常可归因于心房颤动,也可由与心肌炎相关的心内血栓形成引起。CBV,涉及多达40%的急性心肌炎病例,与心肌细胞结合,引发炎症和潜在的血栓形成。心肌炎引起的高凝状态会增加血栓栓塞事件的风险,使临床过程复杂化。
CBV心肌炎存在心力衰竭的风险,心肌病,和血栓栓塞并发症,如栓塞性中风。对并发症的警惕监测和及时管理至关重要,因为主要疾病治疗仍然主要是支持性的。该病例强调需要提高认识和进一步研究,以了解病毒性心肌炎和栓塞性中风之间的复杂关系。
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