PDF(Pubmed)
Abstract：
UNASSIGNED: Published literature suggests that sleep duration and quality may be affected in adults with chronic kidney disease. However, the relationship between these two entities remains a matter of debate. The objective of this systematic review and meta-analysis is to assess the effect of sleep duration and quality on chronic kidney disease.
UNASSIGNED: A systematic review of the Medline/PubMed, Embase, Cochrane Library, and CINAHL databases was conducted for articles pertaining to the association between sleep duration and quality on chronic kidney disease. The main outcome was the hazard/risk ratio of chronic kidney disease in patients of varying sleep durations and quality.
UNASSIGNED: In total, 42 studies (2 613 971 patients) with a mean age of 43.55 ± 14.01 years were included in the meta-analysis. Compared with a reference range of 7 to 8 hours of sleep, short sleep durations of ≤4 hours (RR 1.41, 95% CI: 1.16 to 1.71, P < 0.01), ≤5 hours (RR 1.46, 95% CI: 1.22 to 1.76, P < 0.01), ≤6 hours (RR 1.18, 95% CI: 1.09 to 1.29, P < 0.01), and ≤7 hours (RR 1.19, 95% CI: 1.12 to 1.28, P < 0.01) were significantly associated with an increased risk of incident chronic kidney disease. Long sleep durations of ≥8 hours (RR 1.15, 95% CI: 1.03 to 1.28, P < 0.01) and ≥9 hours (RR 1.46, 95% CI: 1.28 to 1.68, P < 0.01) were also significantly associated with an increased risk of incident chronic kidney disease. Meta-regression did not find any significant effect of age, gender, geographical region, and BMI and an association with sleep duration and risk of incident chronic kidney disease.
UNASSIGNED: Both short and long sleep durations were significantly associated with a higher risk of chronic kidney disease. Interventions targeted toward achieving an optimal duration of sleep may reduce the risk of incident chronic kidney disease.
UNASSIGNED: A systematic review of the Medline/PubMed, Embase, Cochrane Library, and CINAHL databases was conducted for articles pertaining to the association between sleep duration and quality on chronic kidney disease. The main outcome was the hazard/risk ratio of chronic kidney disease in patients of varying sleep durations and quality.
UNASSIGNED: In total, 42 studies (2 613 971 patients) with a mean age of 43.55 ± 14.01 years were included in the meta-analysis. Compared with a reference range of 7 to 8 hours of sleep, short sleep durations of ≤4 hours (RR 1.41, 95% CI: 1.16 to 1.71, P < 0.01), ≤5 hours (RR 1.46, 95% CI: 1.22 to 1.76, P < 0.01), ≤6 hours (RR 1.18, 95% CI: 1.09 to 1.29, P < 0.01), and ≤7 hours (RR 1.19, 95% CI: 1.12 to 1.28, P < 0.01) were significantly associated with an increased risk of incident chronic kidney disease. Long sleep durations of ≥8 hours (RR 1.15, 95% CI: 1.03 to 1.28, P < 0.01) and ≥9 hours (RR 1.46, 95% CI: 1.28 to 1.68, P < 0.01) were also significantly associated with an increased risk of incident chronic kidney disease. Meta-regression did not find any significant effect of age, gender, geographical region, and BMI and an association with sleep duration and risk of incident chronic kidney disease.
UNASSIGNED: Both short and long sleep durations were significantly associated with a higher risk of chronic kidney disease. Interventions targeted toward achieving an optimal duration of sleep may reduce the risk of incident chronic kidney disease.
摘要：
■发表的文献表明，患有慢性肾病的成年人的睡眠时间和质量可能会受到影响。然而,这两个实体之间的关系仍然是一个争论的问题。本系统评价和荟萃分析的目的是评估睡眠时间和质量对慢性肾脏病的影响。
■对Medline/PubMed的系统评价，Embase,科克伦图书馆,和CINAHL数据库对慢性肾脏病患者的睡眠时间和睡眠质量相关文章进行了研究.主要结果是不同睡眠时间和质量的慢性肾脏病患者的风险/风险比。
■总共，42项研究（2.613.971例患者），平均年龄为43.55±14.01岁，纳入荟萃分析。与7到8小时睡眠的参考范围相比，短睡眠时间≤4小时（RR1.41，95％CI：1.16至1.71，P<0.01），≤5小时(RR1.46,95%CI:1.22~1.76,P<0.01),≤6小时(RR1.18,95%CI:1.09~1.29,P<0.01),≤7小时(RR1.19,95%CI:1.12~1.28,P<0.01)与慢性肾脏病发病风险增加显著相关。长睡眠时间≥8小时(RR1.15,95%CI:1.03~1.28,P<0.01)和≥9小时(RR1.46,95%CI:1.28~1.68,P<0.01)也与慢性肾脏病发病风险增加显著相关。Meta回归没有发现年龄的显著影响，性别,地理区域,和BMI以及与睡眠时间和慢性肾脏病发病风险的关系。
■短睡眠时间和长睡眠时间均与慢性肾病的高风险显著相关。以达到最佳睡眠持续时间为目标的干预措施可能会降低慢性肾脏疾病的风险。
■对Medline/PubMed的系统评价，Embase,科克伦图书馆,和CINAHL数据库对慢性肾脏病患者的睡眠时间和睡眠质量相关文章进行了研究.主要结果是不同睡眠时间和质量的慢性肾脏病患者的风险/风险比。
■总共，42项研究（2.613.971例患者），平均年龄为43.55±14.01岁，纳入荟萃分析。与7到8小时睡眠的参考范围相比，短睡眠时间≤4小时（RR1.41，95％CI：1.16至1.71，P<0.01），≤5小时(RR1.46,95%CI:1.22~1.76,P<0.01),≤6小时(RR1.18,95%CI:1.09~1.29,P<0.01),≤7小时(RR1.19,95%CI:1.12~1.28,P<0.01)与慢性肾脏病发病风险增加显著相关。长睡眠时间≥8小时(RR1.15,95%CI:1.03~1.28,P<0.01)和≥9小时(RR1.46,95%CI:1.28~1.68,P<0.01)也与慢性肾脏病发病风险增加显著相关。Meta回归没有发现年龄的显著影响，性别,地理区域,和BMI以及与睡眠时间和慢性肾脏病发病风险的关系。
■短睡眠时间和长睡眠时间均与慢性肾病的高风险显著相关。以达到最佳睡眠持续时间为目标的干预措施可能会降低慢性肾脏疾病的风险。
