PDF(Pubmed)
Abstract：
This research was conducted to examine the impact of Wei Qi Booster (WQB) on immune parameters and anti-oxidative function in aged mice. Fifty aged mice were randomly assigned to five different groups. Group A was designated as the control group. Mice in Group B were receiving Levamisole at 10 mg/kg body weight. Each mouse in groups C, D and E received 0.1, 1, and 2% WQB, respectively. Another ten young mice, designated as group F, were fed regularly. The mice were fed according to the above methods for 28 days. Results showed that relative to the control group, the body weight and immune organs indexes experienced a substantial rise in the group with 1% WQB. In addition, 1% WQB could improve the activity of SOD and reduce the MDA levels. Expressions of CD4 and sIgA increased while CD8 decreased in the jejunum of aged mice treated with WQB. IL2 and IFN-γ levels increased in the 1% WQB group, showing no notable difference compared to the young mice group. The results demonstrated that WQB can elevate immune levels and enhance anti-oxidative functions in aged mice.
摘要：
本研究旨在研究胃气助推器（WQB）对老年小鼠免疫参数和抗氧化功能的影响。将50只老年小鼠随机分配到五个不同的组。将A组指定为对照组。B组的小鼠接受10mg/kg体重的左旋咪唑。C组中的每只老鼠，D和E收到0.1％，1％和2％的WQB，分别。又有十只小老鼠,指定为F组，定期喂食。根据上述方法喂养小鼠28天。结果表明,相对于对照组,1％WQB组的体重和免疫器官指数大幅上升。此外,1%WQB能提高SOD活性，降低MDA水平。WQB处理的老年小鼠空肠中CD4和sIgA的表达增加，而CD8降低。IL2和IFN-γ水平在1%WQB组中增加，与年轻小鼠组相比没有显着差异。结果表明，WQB可以提高衰老小鼠的免疫水平并增强抗氧化功能。
