钙敏感受体与 KIF11 相互作用通过 BRCA1 / cyclin B1 通路增强肺腺癌顺铂耐药.
关键词: BRCA1 CaSR KIF11. chemoresistance cyclin B1 lung adenocarcinoma
Mesh : Humans Cisplatin / therapeutic use pharmacology Receptors, Calcium-Sensing / metabolism genetics Adenocarcinoma of Lung / metabolism drug therapy genetics BRCA1 Protein / metabolism genetics Drug Resistance, Neoplasm Cyclin B1 / metabolism genetics Lung Neoplasms / metabolism drug therapy genetics Cell Line, Tumor Kinesins / metabolism genetics Animals Mice Mice, Nude Female Antineoplastic Agents / pharmacology therapeutic use Male Mice, Inbred BALB C
来 源:
DOI:10.7150/ijbs.92046
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