发现一部具有高度特异性的小说 ,全人 PSCA 抗体及其作为抗体 - 药物偶联物在前列腺癌中的应用。
关键词: Antibody drug conjugate PSCA fully human antibody monomethyl auristatin E prostate cancer tumor xenograft mouse model
Mesh : Humans Male Prostatic Neoplasms / drug therapy pathology immunology Immunoconjugates / pharmacology Animals Antigens, Neoplasm / immunology Mice GPI-Linked Proteins / immunology Neoplasm Proteins / immunology antagonists & inhibitors Xenograft Model Antitumor Assays Cell Line, Tumor Oligopeptides / immunology pharmacology Immunoglobulin G / immunology Antibodies, Monoclonal / immunology pharmacology
来 源:
DOI:10.1080/19420862.2024.2387240
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