关键词: HIV acquired immunodeficiency syndrome adiposity hand strength heart disease risk factors mortality.

来  源:   DOI:10.2174/011570162X306973240802104449

Abstract:
HIV infection is a worldwide epidemic. Antiretroviral therapy allows people living with HIV (PLHIV) increased longevity and a better quality of life. Among the various ways of monitoring the clinical evolution of PLHIV, handgrip strength (HGS) is a promising strategy, as this test can be used to assess the health condition quickly and at a low cost. In this sense, the present study aims to describe, through a literature review, the relationship between HGS and the clinical evolution of PLHIV, especially with morbimortality. Initially, it is highlighted that aging, HIV infection, and excess body fat are related to the loss of HGS in PLHIV. Furthermore, PLHIV is more likely to present cardiometabolic diseases that can be aggravated by reduced HGS. Thus, in people without positive HIV serology, low HGS indirectly, through the presence of risk factors or cardiometabolic diseases, or directly increases the chance of mortality. In conclusion, the lack of studies on this topic for PLHIV is highlighted, and more longitudinal studies, including control groups, are needed.
摘要:
艾滋病毒感染是一种世界性流行病。抗逆转录病毒疗法可以使艾滋病毒感染者(PLHIV)寿命延长,生活质量更好。在监测PLHIV临床演变的各种方法中,握力(HGS)是一种有前途的策略,因为该测试可用于以低成本快速评估健康状况。在这个意义上,本研究旨在描述,通过文献综述,HGS与PLHIV临床进化之间的关系,尤其是病态。最初,它强调了衰老,HIV感染,和过量的身体脂肪与PLHIV中HGS的损失有关。此外,PLHIV更有可能出现心脏代谢疾病,这些疾病可以通过降低HGS而加重。因此,在没有艾滋病毒血清学阳性的人中,间接低HGS,通过存在危险因素或心脏代谢疾病,或直接增加死亡的机会。总之,强调缺乏对PLHIV的研究,和更多的纵向研究,包括对照组,是需要的。
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