Abstract：
OBJECTIVE: To evaluate the diagnostic performance and image quality of accelerated Turbo Spin Echo sequences using deep-learning (DL) reconstructions compared to conventional sequences in knee and ankle MRIs of children and young adults.
METHODS: IRB-approved prospective study consisting of 49 MRIs from 48 subjects (10 males, mean age 16.4 years, range 7-29 years), with each MRI consisting of both conventional and DL sequences. Sequences were evaluated blindly to determine predictive values, sensitivity, and specificity of DL sequences using conventional sequences and knee arthroscopy (if available) as references. Physeal patency and appearance were evaluated. Qualitative parameters were compared. Presence of undesired image alterations was assessed.
RESULTS: The prevalence of abnormal findings in the knees and ankles were 11.7% (75/640), and 11.5% (19/165), respectively. Using conventional sequences as reference, sensitivity and specificity of DL sequences in knees were 90.7% and 99.3%, and in ankles were 100.0% and 100.0%. Using arthroscopy as reference, sensitivity and specificity of DL sequences were 80.0% and 95.8%, and of conventional sequences were 80.0% and 97.9%. Agreement of physeal status was 100.0%. DL sequences were qualitatively \"same-or-better\" compared to conventional (p < 0.032), except for pixelation artifact for the PDFS sequence (p = 0.233). No discrete image alteration was identified in the knee DL sequences. In the ankle, we identified one DL artifact involving a tendon (0.8%, 1/125). DL sequences were faster than conventional sequences by a factor of 2 (p < 0.001).
CONCLUSIONS: In knee and ankle MRIs, DL sequences provided similar diagnostic performance and \"same-or-better\" image quality than conventional sequences at half the acquisition time.
METHODS: IRB-approved prospective study consisting of 49 MRIs from 48 subjects (10 males, mean age 16.4 years, range 7-29 years), with each MRI consisting of both conventional and DL sequences. Sequences were evaluated blindly to determine predictive values, sensitivity, and specificity of DL sequences using conventional sequences and knee arthroscopy (if available) as references. Physeal patency and appearance were evaluated. Qualitative parameters were compared. Presence of undesired image alterations was assessed.
RESULTS: The prevalence of abnormal findings in the knees and ankles were 11.7% (75/640), and 11.5% (19/165), respectively. Using conventional sequences as reference, sensitivity and specificity of DL sequences in knees were 90.7% and 99.3%, and in ankles were 100.0% and 100.0%. Using arthroscopy as reference, sensitivity and specificity of DL sequences were 80.0% and 95.8%, and of conventional sequences were 80.0% and 97.9%. Agreement of physeal status was 100.0%. DL sequences were qualitatively \"same-or-better\" compared to conventional (p < 0.032), except for pixelation artifact for the PDFS sequence (p = 0.233). No discrete image alteration was identified in the knee DL sequences. In the ankle, we identified one DL artifact involving a tendon (0.8%, 1/125). DL sequences were faster than conventional sequences by a factor of 2 (p < 0.001).
CONCLUSIONS: In knee and ankle MRIs, DL sequences provided similar diagnostic performance and \"same-or-better\" image quality than conventional sequences at half the acquisition time.
摘要：
目的：评估使用深度学习（DL）重建的加速TurboSpinEcho序列的诊断性能和图像质量，与儿童和年轻人的膝盖和脚踝MRI的常规序列相比。
方法：IRB批准的前瞻性研究，包括来自48名受试者的49个MRI（10名男性，平均年龄16.4岁，7-29年)，每个MRI由常规和DL序列组成。盲目评估序列以确定预测值，灵敏度,使用常规序列和膝关节镜（如果有）作为参考的DL序列和特异性。评估了Physeal的通畅性和外观。比较定性参数。评估不期望的图像改变的存在。
结果：膝关节和脚踝异常发现的患病率为11.7％（75/640），和11.5%(19/165)，分别。使用常规序列作为参考，膝关节DL序列的敏感性和特异性分别为90.7%和99.3%,脚踝分别为100.0%和100.0%。以关节镜为参考，DL序列的敏感性和特异性分别为80.0%和95.8%,常规序列分别为80.0%和97.9%。physeal状态的一致性为100.0％。与常规序列相比，DL序列在质量上“相同或更好”（p<0.032），除了PDFS序列的像素化伪影(p=0.233)。在膝关节DL序列中未发现离散图像改变。在脚踝，我们确定了一个涉及肌腱的DL伪影(0.8%，1/125).DL序列比常规序列快2倍(p<0.001)。
结论：在膝关节和踝关节MRI中，DL序列在一半的采集时间内提供了与传统序列相似的诊断性能和“相同或更好”的图像质量。
方法：IRB批准的前瞻性研究，包括来自48名受试者的49个MRI（10名男性，平均年龄16.4岁，7-29年)，每个MRI由常规和DL序列组成。盲目评估序列以确定预测值，灵敏度,使用常规序列和膝关节镜（如果有）作为参考的DL序列和特异性。评估了Physeal的通畅性和外观。比较定性参数。评估不期望的图像改变的存在。
结果：膝关节和脚踝异常发现的患病率为11.7％（75/640），和11.5%(19/165)，分别。使用常规序列作为参考，膝关节DL序列的敏感性和特异性分别为90.7%和99.3%,脚踝分别为100.0%和100.0%。以关节镜为参考，DL序列的敏感性和特异性分别为80.0%和95.8%,常规序列分别为80.0%和97.9%。physeal状态的一致性为100.0％。与常规序列相比，DL序列在质量上“相同或更好”（p<0.032），除了PDFS序列的像素化伪影(p=0.233)。在膝关节DL序列中未发现离散图像改变。在脚踝，我们确定了一个涉及肌腱的DL伪影(0.8%，1/125).DL序列比常规序列快2倍(p<0.001)。
结论：在膝关节和踝关节MRI中，DL序列在一半的采集时间内提供了与传统序列相似的诊断性能和“相同或更好”的图像质量。
