关键词: Laryngeal diseases Laryngeal tuberculosis Tuberculosis

Mesh : Humans Tuberculosis, Laryngeal / diagnosis drug therapy Male Female Adult Middle Aged Laryngoscopy Hoarseness / etiology Tuberculosis, Pulmonary / diagnosis drug therapy Antitubercular Agents / therapeutic use Aged Vocal Cords / pathology Smoking / adverse effects Retrospective Studies Diagnosis, Differential Laryngopharyngeal Reflux / diagnosis

来  源:   DOI:10.1016/j.ijtb.2024.07.001

Abstract:
BACKGROUND: Laryngeal involvement is rare in tuberculosis, representing around 1% of all cases of this infection worldwide. Given the larynx\' location in the airway, this form of tuberculosis is of particular importance because it is highly contagious. With our hospital being in a high tuberculosis burden area, we propose to characterize the clinical presentation, evolution, and laryngoscopy findings of a series of laryngeal tuberculosis cases in order to reduce misdiagnosis.
METHODS: Epidemiological and clinical data from 10 patients diagnosed with laryngeal tuberculosis in the Otorhinolaryngology department of (Blinded for manuscript) between January 2011 and December 2021 were retrieved and analyzed.
RESULTS: There were eight males and two females. Seven patients had a history of smoking and alcohol abuse and four had silicosis. Hoarseness was the most reported symptom (n = 9). The most frequent site of involvement were the true vocal cords (n = 6). All patients but one had concomitant active pulmonary tuberculosis. Patients had full resolution of laryngeal symptoms between 4 and 16 weeks after initiating antituberculosis treatment.
CONCLUSIONS: Laryngeal tuberculosis is indeed a great deceiver. On one hand it can look like a simple polypoid lesion or simulate laryngopharyngeal reflux; but on the other hand its risk factors, symptoms and appearance simulate laryngeal carcinoma like no other. Since most patients present with concomitant pulmonary tuberculosis, all suspect laryngeal lesions should perform a chest radiograph prior to rigid laryngoscopy. Antituberculosis treatment is effective in both alleviating symptoms and reducing the risk of transmission.
摘要:
背景:喉部受累在结核病中是罕见的,约占全球所有这种感染病例的1%。鉴于喉部在气道中的位置,这种形式的结核病特别重要,因为它具有高度传染性。由于我们医院处于结核病高负担地区,我们建议表征临床表现,进化,和喉镜检查发现的一系列喉结核病例,以减少误诊。
方法:检索并分析2011年1月至2021年12月耳鼻咽喉科诊断为喉结核的10例患者的流行病学和临床资料。
结果:有8名男性和2名女性。7例患者有吸烟和酗酒史,4例有矽肺。声音嘶哑是报告最多的症状(n=9)。最常见的受累部位是真实的声带(n=6)。除一名患者外,所有患者均伴有活动性肺结核。开始抗结核治疗后4至16周,患者的喉症状完全缓解。
结论:喉结核确实是一个很大的欺骗者。一方面,它看起来像一个简单的息肉样病变或模拟咽喉反流;但另一方面,其危险因素,症状和外观模拟喉癌没有像其他。由于大多数患者同时患有肺结核,所有可疑的喉部病变均应在刚性喉镜检查前进行胸部X光检查.抗结核治疗在缓解症状和降低传播风险方面都是有效的。
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