Abstract：
UNASSIGNED: To evaluate the impact of levonorgestrel-releasing intrauterine device (LNG-IUD) use on the incidence of acne in adolescents and young women.
UNASSIGNED: A narrative review was conducted in PubMed, Embase, Cochrane, and SciELO assessing the incidence of acne in adolescents and young women using LNG-IUD (13.5, or 19.5 mg, or 52 mg). Cohort, cross-sectional studies, clinical trials, and meta-analyses were included, without a date limit. Studies that didn\'t evaluate women in the age of interest were excluded. Only articles in English were selected.
UNASSIGNED: Nine articles were included in this narrative review. Only clinical trials, cohort studies, and cross-sectional studies were evaluated. Two cross-sectional studies evaluated the incidence of acne in women using any contraceptive methods, with the incidence of acne being 36% in women aged 17 to 47 using LNG-IUD in one study. In another study, acne incidence ranged from 2 to 8% in women using any contraceptive methods, with higher rates in younger women and LNG-IUD users. The incidence of acne varies and participants between 16 to 35 years were more likely to report new acne or worsening of pre-existing acne. In a prospective cohort study of women between 16 and 24 years, acne was a common adverse effect, with 44% in the first year.
UNASSIGNED: The data indicate variability in the incidence of acne among LNG-IUD users, with a higher prevalence observed in younger women. Further research should focus on the effects of LNG-IUD on acne in young populations, with rigorous study designs and consideration of previous contraceptive use.
The levonorgestrel-releasing intrauterine device (LNG-IUD) is an important tool in the prevention of unplanned pregnancies in adolescents and young women. Acne is a possible adverse effect that could lead to discontinuation of the method.
UNASSIGNED: A narrative review was conducted in PubMed, Embase, Cochrane, and SciELO assessing the incidence of acne in adolescents and young women using LNG-IUD (13.5, or 19.5 mg, or 52 mg). Cohort, cross-sectional studies, clinical trials, and meta-analyses were included, without a date limit. Studies that didn\'t evaluate women in the age of interest were excluded. Only articles in English were selected.
UNASSIGNED: Nine articles were included in this narrative review. Only clinical trials, cohort studies, and cross-sectional studies were evaluated. Two cross-sectional studies evaluated the incidence of acne in women using any contraceptive methods, with the incidence of acne being 36% in women aged 17 to 47 using LNG-IUD in one study. In another study, acne incidence ranged from 2 to 8% in women using any contraceptive methods, with higher rates in younger women and LNG-IUD users. The incidence of acne varies and participants between 16 to 35 years were more likely to report new acne or worsening of pre-existing acne. In a prospective cohort study of women between 16 and 24 years, acne was a common adverse effect, with 44% in the first year.
UNASSIGNED: The data indicate variability in the incidence of acne among LNG-IUD users, with a higher prevalence observed in younger women. Further research should focus on the effects of LNG-IUD on acne in young populations, with rigorous study designs and consideration of previous contraceptive use.
The levonorgestrel-releasing intrauterine device (LNG-IUD) is an important tool in the prevention of unplanned pregnancies in adolescents and young women. Acne is a possible adverse effect that could lead to discontinuation of the method.
摘要：
■评估使用左炔诺孕酮宫内节育器（LNG-IUD）对青少年和年轻女性痤疮发生率的影响。
■在PubMed中进行了叙述性审查，Embase,科克伦,和SciELO评估使用LNG-IUD的青少年和年轻女性的痤疮发生率（13.5或19.5毫克，或52毫克)。队列,横断面研究，临床试验,并纳入荟萃分析，没有日期限制。没有评估感兴趣年龄女性的研究被排除在外。只选择了英文文章。
■这篇叙述性综述包括9篇文章。只有临床试验,队列研究，和横断面研究进行了评估。两项横断面研究评估了使用任何避孕方法的女性痤疮的发生率，在一项研究中，使用液化天然气宫内节育器的17至47岁女性中痤疮的发生率为36％。在另一项研究中,在使用任何避孕方法的女性中，痤疮的发病率为2％至8％，年轻女性和液化天然气宫内节育器使用者的比率更高。痤疮的发生率各不相同，16至35岁的参与者更有可能报告新的痤疮或先前存在的痤疮恶化。在一项16至24岁女性的前瞻性队列研究中，痤疮是一种常见的不良反应,第一年为44%。
■数据表明，液化天然气宫内节育器使用者的痤疮发生率存在差异，在年轻女性中观察到较高的患病率。进一步的研究应该集中在液化天然气宫内节育器对年轻人群痤疮的影响，严格的研究设计和以前使用避孕药具的考虑。
释放左炔诺孕酮的宫内节育器（LNG-IUD）是预防青少年和年轻女性意外怀孕的重要工具。痤疮是可能导致该方法停止的可能的不利影响。
■在PubMed中进行了叙述性审查，Embase,科克伦,和SciELO评估使用LNG-IUD的青少年和年轻女性的痤疮发生率（13.5或19.5毫克，或52毫克)。队列,横断面研究，临床试验,并纳入荟萃分析，没有日期限制。没有评估感兴趣年龄女性的研究被排除在外。只选择了英文文章。
■这篇叙述性综述包括9篇文章。只有临床试验,队列研究，和横断面研究进行了评估。两项横断面研究评估了使用任何避孕方法的女性痤疮的发生率，在一项研究中，使用液化天然气宫内节育器的17至47岁女性中痤疮的发生率为36％。在另一项研究中,在使用任何避孕方法的女性中，痤疮的发病率为2％至8％，年轻女性和液化天然气宫内节育器使用者的比率更高。痤疮的发生率各不相同，16至35岁的参与者更有可能报告新的痤疮或先前存在的痤疮恶化。在一项16至24岁女性的前瞻性队列研究中，痤疮是一种常见的不良反应,第一年为44%。
■数据表明，液化天然气宫内节育器使用者的痤疮发生率存在差异，在年轻女性中观察到较高的患病率。进一步的研究应该集中在液化天然气宫内节育器对年轻人群痤疮的影响，严格的研究设计和以前使用避孕药具的考虑。
释放左炔诺孕酮的宫内节育器（LNG-IUD）是预防青少年和年轻女性意外怀孕的重要工具。痤疮是可能导致该方法停止的可能的不利影响。
