关键词: Immunocompetent Legionella Legionellosis Lymphadenitis

来  源:   DOI:10.1016/j.idcr.2024.e02023   PDF(Pubmed)

Abstract:
UNASSIGNED: Extrapulmonary legionella disease is rare and occasionally reported in immunocompromised patients; it includes lymphadenitis, panniculitis, hepatitis, atrio-ventricular block, arthritis, prosthetic valve endocarditis and myocarditis. In this article, we report a rare case of legionella suppurative lymphadenitis in an immunocompetent patient.
UNASSIGNED: 53-year-old female patient from the Philippines, non-smoker, previously healthy who presented to our facility for chills and respiratory distress following a course of corticosteroid intake. She was admitted for respiratory failure and septic shock, and was diagnosed with legionella infection associated with extrapulmonary dissemination (lymphadenitis) leading to her death 72 h after admission.
UNASSIGNED: Legionella is an important cause of community acquired pneumonia (CAP) and a delay in appropriate antibiotic therapy was associated with an increased mortality rate. Since legionnaire\'s disease is indistinguishable from other forms of pneumonia without diagnostic testing, empiric antibiotic therapy regimen should cover legionella species. In unfortunate cases, a delay in the diagnosis and treatment may lead to extrapulmonary manifestations such as lymphadenitis and will be associated with worse patient outcomes.
UNASSIGNED: Legionella is an important cause of community acquired pneumonia which if left untreated can become complicated with extrapulmonary manifestations such as lymphadenitis and become eventually fatal to patients. A prompt early diagnosis and appropriate antimicrobial therapy covering legionella should be considered whenever treating community acquired pneumonia.
摘要:
肺外军团菌病很少见,偶尔在免疫功能低下的患者中报告;包括淋巴结炎,脂膜炎,肝炎,房室传导阻滞,关节炎,人工瓣膜心内膜炎和心肌炎。在这篇文章中,我们报道了一例免疫功能正常的军团菌化脓性淋巴结炎的罕见病例。
来自菲律宾的53岁女性患者,非吸烟者,以前健康的人在服用皮质类固醇一个疗程后出现寒战和呼吸窘迫。她因呼吸衰竭和感染性休克入院,并被诊断为军团菌感染与肺外播散(淋巴结炎)相关,导致入院后72小时死亡。
军团菌是社区获得性肺炎(CAP)的重要原因,适当抗生素治疗的延迟与死亡率增加有关。由于没有诊断测试,军团病与其他形式的肺炎无法区分,经验性抗生素治疗方案应涵盖军团菌。在不幸的情况下,诊断和治疗的延迟可能导致肺外表现,如淋巴结炎,并与患者预后恶化有关。
军团菌是社区获得性肺炎的重要原因,如果不及时治疗,可能会并发肺外表现,如淋巴结炎,并最终导致患者死亡。每当治疗社区获得性肺炎时,应考虑及时早期诊断和适当的抗菌治疗,包括军团菌。
公众号