PDF(Pubmed)
Abstract：
BACKGROUND: Lidocaine/prilocaine (EMLA) cream is a local anesthetic that is applied to the skin or mucosa during painful therapeutic procedures with few reported side effects.
METHODS: Here, we report the use of dermatoscopy to identify a case of erythema with purpura, a rare side effect, after the application of 5% EMLA cream.
CONCLUSIONS: We conclude that erythema with purpura is caused by irritation and toxicity associated with EMLA, but the specific mechanism by which the toxic substance affects skin blood vessels is unclear. In response to this situation and for cosmetic needs, we recommend tranexamic acid, in addition to routine therapy, to prevent changes in pigmentation in patients with dermatitis.
METHODS: Here, we report the use of dermatoscopy to identify a case of erythema with purpura, a rare side effect, after the application of 5% EMLA cream.
CONCLUSIONS: We conclude that erythema with purpura is caused by irritation and toxicity associated with EMLA, but the specific mechanism by which the toxic substance affects skin blood vessels is unclear. In response to this situation and for cosmetic needs, we recommend tranexamic acid, in addition to routine therapy, to prevent changes in pigmentation in patients with dermatitis.
摘要：
背景：利多卡因/丙胺卡因（EMLA）乳膏是一种局部麻醉药，在痛苦的治疗过程中应用于皮肤或粘膜，几乎没有报道的副作用。
方法：这里，我们报告使用皮肤镜检查来确定一例红斑伴紫癜，一种罕见的副作用,后应用5%EMLA乳膏。
结论：我们得出结论，紫癜性红斑是由与EMLA相关的刺激和毒性引起的，但是毒性物质影响皮肤血管的具体机制尚不清楚。为了应对这种情况和化妆品的需求，我们推荐氨甲环酸,除了常规治疗，防止皮炎患者色素沉着的变化。
方法：这里，我们报告使用皮肤镜检查来确定一例红斑伴紫癜，一种罕见的副作用,后应用5%EMLA乳膏。
结论：我们得出结论，紫癜性红斑是由与EMLA相关的刺激和毒性引起的，但是毒性物质影响皮肤血管的具体机制尚不清楚。为了应对这种情况和化妆品的需求，我们推荐氨甲环酸,除了常规治疗，防止皮炎患者色素沉着的变化。
