PDF(Pubmed)
Abstract：
Linear morphea is the most disabling subtype of morphea, which may cause a series of excutaneous manifestations and sequelae. To futher explore the clinical characteristics of linear morphea, we conducted a retrospective study of 22 patients diagnosed with linear morphea in our department during the past 2 years. Their baseline clinical information, skin manifestations, complications and therapeutic effect were analyzed. Here, we report six cases of a special linear morphea, usually occurring on the unilateral upper limbs of young women, spreading along the distribution of the radial nerve and frequently progressing across the joint, which increases the incidence of neuromusculoskeletal disorders. Instead of traditional topical drugs, a combination of systemic prednisone and methotrexate improved their skin lesions and complications. Recognition of this special type of linear morphea enables earlier diagnosis and active treatment plan, which contributes to ameliorate the symptoms and avoid functional sequelae.
摘要：
线形硬伤是硬伤最致残的亚型,这可能会导致一系列的异常表现和后遗症。为进一步探讨线形硬伤的临床特点,我们对过去2年来在我们科室诊断为线性角膜病的22例患者进行了回顾性研究.他们的基线临床信息，皮肤表现，对并发症及治疗效果进行分析。这里,我们报告了6例特殊的线形性角膜病，通常发生在年轻女性的单侧上肢，沿着桡神经的分布传播，并经常在关节上传播，这增加了神经肌肉骨骼疾病的发病率。而不是传统的外用药物，全身泼尼松和甲氨蝶呤联合治疗可改善其皮肤损伤和并发症.识别这种特殊类型的线性角膜能够早期诊断和积极的治疗计划，这有助于改善症状并避免功能性后遗症。
