UNASSIGNED: A 34-year-old man presented with progressive left eye proptosis for 4 months. Initial evaluation and imaging led to a high suspicion of LGACC, which was confirmed after an eye-sparing excision of the left orbital tumor. The patient declined to undergo postoperative radiotherapy, which was recommended after the surgery. Thus, despite surgical intervention, the patient experienced tumor recurrence 3 months post-surgery, leading to orbital exenteration. Pathological examination confirmed the presence of poorly differentiated LGACC.This time the patient underwent postoperative radiotherapy, as recommended. However, despite local control, the patient developed an intracranial metastasis within a year.
UNASSIGNED: LGACC presents significant diagnostic and therapeutic challenges owing to its insidious onset, lack of specific symptoms, and high potential for recurrence and metastasis. Thus, this case emphasizes the need for early diagnosis, aggressive treatment, and adherence to postoperative adjuvant therapy to improve patient outcomes. Future research should focus on understanding the pathogenesis of LGACC and on developing standardized diagnostic and treatment protocols to enhance patient prognosis and survival.
■一名34岁男子出现进行性左眼眼球突出4个月。初步评估和成像导致对LGACC的高度怀疑,这是在保留眼睛切除左眶肿瘤后证实的。病人拒绝接受术后放疗,这是手术后推荐的。因此,尽管有手术干预,患者在手术后3个月出现肿瘤复发,导致眼眶放血.病理检查证实存在低分化LGACC。这次病人接受了术后放疗,如推荐。然而,尽管有本地控制,患者在一年内出现颅内转移。
■LGACC由于其隐匿的发作而提出了重大的诊断和治疗挑战,缺乏特定的症状,复发和转移的可能性很高。因此,这个案例强调了早期诊断的必要性,积极治疗,并坚持术后辅助治疗以改善患者预后。未来的研究应该集中在了解LGACC的发病机制和发展标准化的诊断和治疗方案,以提高患者的预后和生存。