关键词: DVT deep vein thrombosis high-risk pediatric patient risk factor

来  源:   DOI:10.2478/jccm-2024-0024   PDF(Pubmed)

Abstract:
UNASSIGNED: Although rarely diagnosed in the pediatric population, deep vein thrombosis (DVT) is experiencing a growing incidence, while continuously acquiring different nuances due to the widening range of risk factors and lifestyle changes in children and adolescents.
UNASSIGNED: A 17-year-old female within four weeks after child delivery was admitted to our clinic due to a six-month history of pain in the left hypochondriac region. After a thorough evaluation, the presence of a benign splenic cyst was revealed, which was later surgically removed. Following the intervention, the patient developed secondary thrombocytosis and bloodstream infection which, together with pre-existing risk factors (obesity, compressive effect of a large cyst, the postpartum period, the presence of a central venous catheter, recent surgery, and post-operative mobilization difficulties) led to the occurrence of extensive DVT, despite anticoagulant prophylaxis and therapy with low-molecular-weight heparin.
UNASSIGNED: DVT raises many challenges for the pediatrician, requiring a personalized approach. Although rare, pediatric patients with multiple concomitant high-risk factors should benefit from interdisciplinary care as DVT may not respond to standard therapy in such cases and rapidly become critical. Continual efforts to better understand and treat this condition will contribute to improved outcomes for pediatric patients affected by DVT.
摘要:
尽管在儿科人群中很少被诊断出,深静脉血栓形成(DVT)的发病率越来越高,同时由于儿童和青少年的风险因素和生活方式变化的范围不断扩大而不断获得不同的细微差别。
一名17岁的女性在分娩后4周内因左侧软骨缺损区域有6个月的疼痛史而入院。经过全面评估,发现了良性脾囊肿的存在,后来被手术切除。干预之后,患者出现继发性血小板增多症和血流感染,连同预先存在的风险因素(肥胖,大囊肿的压缩效果,产后,中心静脉导管的存在,最近的手术,和术后动员困难)导致广泛DVT的发生,尽管抗凝预防和低分子量肝素治疗。
DVT给儿科医生带来了许多挑战,需要个性化的方法。虽然罕见,同时存在多种高危因素的儿科患者应该从跨学科治疗中获益,因为在这种情况下,DVT可能对标准治疗无反应,并迅速变得严重.不断努力更好地了解和治疗这种情况将有助于改善受DVT影响的儿科患者的预后。
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