关键词: Cerebrospinal fluid malabsorption Foramen magnum meningioma Lumbar peritoneal shunt Postoperative hydrocephalus Tumor resection

来  源:   DOI:10.25259/SNI_129_2024   PDF(Pubmed)

Abstract:
UNASSIGNED: Tumors in or near the foramen magnum may cause communicating or non-communicating hydrocephalus (HC), depending on their size and location. Here, an 81-year-old female developed communicating HC following the resection of a meningioma ventral to the foramen magnum.
UNASSIGNED: An 81-year-old female presented with numbness in the left neck and left hemiparesis. The magnetic resonance revealed an 18-mm tumor ventral to the foramen magnum that significantly enlarged over the past 6 months. She underwent total tumor resection but then presented with progressive HC both clinically (i.e., instability of gait with confusion) and radiographically (computed tomography). Following placement of a lumboperitoneal (LP) shunt, symptoms markedly improved. Further, the cerebrospinal fluid (CSF) analysis showed elevated cell counts and protein concentrations, indicating likely \"leakage\" of intratumoral contents postoperatively contributing to the progressive HC.
UNASSIGNED: Patients presenting with acute meningiomas ventral to the foramen magnum may develop postoperative communicating HC attributed to tumor-related CSF leakage of necrotic intratumoral components that can be successfully treated with a LP shunt.
摘要:
大孔内或附近的肿瘤可能会导致交通或非交通性脑积水(HC),取决于它们的大小和位置。这里,一名81岁的女性在切除脑膜瘤腹侧大孔后出现了HC。
一名81岁女性,左颈部麻木,左偏瘫。磁共振检查显示,在过去的6个月中,大孔腹侧有18毫米的肿瘤明显扩大。她接受了全肿瘤切除术,但随后在临床上都出现了进行性HC(即,步态不稳定,伴有混乱)和影像学检查(计算机断层扫描)。在放置腰腹膜(LP)分流术后,症状明显改善。Further,脑脊液(CSF)分析显示细胞计数和蛋白质浓度升高,表明术后肿瘤内内容物的“渗漏”可能导致进行性HC。
患有急性脑膜瘤的患者可能会在术后发生沟通性HC,原因是肿瘤相关的脑脊液坏死瘤内成分渗漏,可以通过LP分流术成功治疗。
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